When basic skincare products stop delivering visible results and your skin consistently looks dull and sallow after seasonal changes or stress, many seek a solution that works from the cellular level upward. Rejuran is South Korea’s most representative PDRN-based skin regeneration treatment — it’s not about surface concealment but about injecting polydeoxyribonucleotides (highly similar to human DNA fragments) into the dermis to activate the skin’s own repair mechanisms.
Rejuran is a patented product by PharmaResearch (South Korea), using PDRN extracted from salmon germ cells — structurally highly similar to human DNA with excellent biocompatibility.
What Is PDRN — Rejuran’s Core Ingredient?
PDRN (Polydeoxyribonucleotide) is a low-molecular-weight DNA fragment extracted from salmon reproductive cells. Once injected into the skin, PDRN activates two key mechanisms:
- Cellular regeneration:Provides nucleotides and nucleosides as DNA synthesis “building blocks,” promoting fibroblast proliferation and collagen production
- Anti-inflammatory repair:Modulates inflammatory mediators, reducing chronic skin inflammation caused by UV and environmental damage
- Angiogenesis:Stimulates micro-capillary formation, improving nutrient delivery and metabolic circulation in the skin
Who Benefits from Full-Face Rejuran?
- Dull, uneven skin tone — skin that lacks radiance even after adequate sleep
- Enlarged pores with rough skin texture (collagen-loss type, not sebum-type)
- Increasing and deepening fine lines (periocular, nasolabial, forehead static lines)
- Reactive, sensitive skin with frequent redness and barrier damage
- Those seeking overall skin health improvement at the cellular level
The Rappoel Rejuran Treatment Process
- Consultation:The doctor assesses skin condition — dryness level, sensitivity status, aging indicators — and designs the injection protocol
- Numbing:Topical anesthetic cream applied for 20–30 minutes
- Injection:Ultra-fine needle delivering micro-doses evenly across the full face — about 15–20 minutes
- Post-treatment:Mild pinpoint redness and swelling on treatment day — makeup and normal activities can resume the following day
Results Timeline and Maintenance
- Immediate post-treatment:Mild healthy flush — like post-exercise glow
- 1–2 weeks:Noticeable improvement in skin radiance and hydration levels
- 4–6 weeks:Peak PDRN activity window — most visible improvement in skin elasticity and fine lines
- Recommended protocol:Initial series of 3 sessions (3–4 weeks apart), followed by maintenance every 6–12 months
Frequently Asked Questions
- Q1: How is Rejuran different from a standard skin booster?
- Standard skin boosters primarily use hyaluronic acid for immediate hydration. Rejuran’s core ingredient is PDRN, which stimulates the skin’s own regenerative repair at the cellular level rather than simply adding moisture.
- Q2: What is the recovery time after Rejuran?
- The treated face will show numerous fine needle marks (injection points) with mild redness and swelling on treatment day, typically resolving within 24 hours. We recommend avoiding makeup on the day of treatment; normal makeup can be applied the following day.
- Q3: Is Rejuran painful?
- Topical anesthesia is applied before treatment. Most patients describe the sensation as mild prickling. Rejuran injections are generally less uncomfortable than hyaluronic acid filler injections.
- Q4: Can sensitive skin types do Rejuran?
- One of Rejuran’s core functions is anti-inflammatory action and barrier repair, making it particularly suitable for sensitive, reactive skin types. However, those with acute inflammation or severe active allergies should consult the doctor first.
- Q5: Do I need ongoing Rejuran sessions to maintain results?
- After completing the initial series of 3 sessions, skin baseline health is significantly elevated. Thereafter, maintenance once every 6–12 months is sufficient.
- Q6: How do I book Rejuran at Rappoel?
- 3-minute walk from Gangnam Station Exit 10 (77 Seocho-daero, 24F, 5F). Book via WeChat (rappoelkr) or Line (rappoelkr).
Clinic Information
- 📍 Address: 5F, 77 Seocho-daero, Seocho-gu, Seoul
- 🚇 Access: Gangnam Station Exit 10, 3-minute walk (Seoul Metro Line 2)
- 🕐 Hours: Mon–Fri 10:00–19:00 | Sat 10:00–17:00
- 💬 Booking: WeChat rappoelkr | Line rappoelkr
Contact Rappoel Dermatology Clinic
📍 77, Seocho-daero, Seocho-gu, Seoul, South Korea
🕐 Mon–Fri 10:00–19:00 · Sat 10:00–17:00
💬 WeChat Main: rappoelkr | WeChat Backup: rappoelkr2 | LINE: rappoelkr
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