After 30, skin collagen declines at roughly 1% per year — the result is thinner, looser, duller skin with enlarged pores and blurred contours. Traditional HA is a ‘filler’ — adding volume where hollowed. Profhilo from Italy takes an entirely different route: it is the world’s first ‘bio-remodelling’ injectable — patented ultra-high concentration pure HA (64mg per ml, 2-3 times typical fillers) that, once injected, does not create volume but spreads through the tissue like a biological signal, directly stimulating new collagen and elastin in the dermis. Concerns it suits: (1) Overall skin laxity and lost elasticity — especially the ‘saggy feel’ of cheeks and jawline. (2) Dull, rough skin with declining skincare response — overall ‘tired’ skin quality. (3) Neck and decolletage fine lines and laxity — zones skincare barely reaches. (4) Mild contour blurring — wanting overall tightening and brightening rather than local filling. (5) Postpartum or post-weight-loss laxity. (6) Natural-look seekers who fear filler puffs and want ‘no one can tell, but I look younger overall.’ Rappoel Dermatology near Gangnam Station, Seoul, provides Profhilo treatment.
Profhilo’s Unique Technology
- Patented thermal stabilization (NAHYCO): Profhilo combines high- and low-molecular HA through a patented thermal process, without any chemical cross-linking agent (BDDE) — extreme purity, superb biocompatibility, minimal allergy risk
- Bio-remodelling: After injection the HA spreads slowly through the tissue, hydrating like a sponge while signaling fibroblasts to ‘get to work’ — stimulating type I and III collagen and elastin production
- 128mg per syringe: 2ml containing 128mg pure HA (64mg/ml) — among the highest concentrations of any skin injectable — ample ‘raw material’ for regeneration per session
- 5-point injection (BAP): The official Bio Aesthetic Points technique — just 5 fixed injection points per side (10 total) let the HA spread naturally across the whole face, avoiding nerve- and vessel-dense zones — fast and safe
- Slow-release duration: The thermally stable structure degrades slowly (about 28 days), continuously stimulating collagen — the result is not instant plumping but firmness that ‘grows in’ over 1-4 weeks
Positioning vs Other Injectables
- Profhilo vs traditional HA filler: Fillers add volume (hollows like tear troughs and cheeks); Profhilo adds no volume but makes the whole face’s skin thicker, firmer, and brighter — local sculpting versus global upgrade
- Profhilo vs skin boosters: Skin boosters hydrate superficially (fast but short-lived, needing frequent sessions); Profhilo works deeper and more concentrated, stimulating collagen rather than just hydration — longer lasting (about 6 months)
- Profhilo vs Rejuran: Rejuran’s salmon DNA (PN) focuses on repair and skin renewal; Profhilo’s HA focuses on firming and brightening — they can be combined (2-4 weeks apart) for ‘repair plus remodeling’
- Profhilo vs Thermage: Thermage stimulates collagen with RF heat energy (device); Profhilo stimulates biologically (injectable) — device tightening and injectable regeneration complement each other
Rappoel Profhilo Protocol
- Consultation (10 min): Skin elasticity testing and laxity assessment → confirm skin condition (dullness/roughness/fine lines) → discuss goals (firmness/glow/overall rejuvenation) → rule out contraindications
- Cleansing and anesthesia (20 min): Makeup removal → alcohol disinfection → topical anesthetic cream (BAP injections are subcutaneous; cream reduces discomfort)
- 5-point injection (10 min): Official BAP technique, 5 points per cheek → slow subcutaneous injection → gentle pressure to stop any bleeding
- Post-care instructions (3 min): No makeup, strenuous exercise, or heat for 24 hours → small papules at injection points absorb and spread within 2-3 days → no massage needed
- Second session: Second injection 4 weeks later (standard course is 2 sessions one month apart) → maintenance single sessions about every 6 months thereafter
The standard Profhilo course is 2 sessions (4 weeks apart); effects emerge 2-4 weeks after the first session — improved firmness, glow, and softened fine lines — peaking 4-8 weeks after course completion and lasting about 6 months. Located 3 minutes from Gangnam Station Exit 10, with seamless English and Chinese consultation.
Frequently Asked Questions
What exactly is Profhilo? How is it different from regular HA filler?
Core differences: (1) Concentration — Profhilo is an ultra-high concentration pure HA (64mg/ml) developed by Italy’s IBSA; typical fillers run about 20-25mg/ml — a 2-3x gap. (2) Cross-linking — regular fillers require the chemical cross-linker BDDE to hold shape and support; Profhilo combines high- and low-molecular HA via patented thermal stabilization (NAHYCO) with zero chemical cross-linker — higher purity and safety. (3) Mechanism — regular HA ‘fills’: it creates volume where injected (nose, lips, hollows); Profhilo ‘bio-remodels’: it spreads through tissue, stimulating collagen and elastin production so the skin itself becomes thicker, firmer, and brighter. (4) Injection method — fillers need multi-point sculpting; Profhilo uses the official 5-point BAP technique, 10 injections covering the whole face. (5) Simple analogy — filler ‘inflates the balloon’; Profhilo ‘replaces it with a new balloon.’ (6) Choosing — local hollows and volume loss choose filler; overall laxity, dullness, and tired skin quality choose Profhilo; the two are often planned together.
What concerns can Profhilo improve? How noticeable is it?
Scope and results: (1) Firming — stimulated collagen and elastin markedly improve skin elasticity, especially the saggy feel of cheeks and jawline, sharpening contour lines. (2) Glow — HA’s powerful hydration plus collagen renewal produces an ‘inside-out’ dewy radiance, improving dullness and sallowness. (3) Fine lines — as the dermis thickens, fine lines under the eyes and on cheeks soften. (4) Pores — improved collagen support makes pores look finer. (5) Neck and decolletage — Profhilo is among the few products officially approved for the neck and chest, clearly improving neck lines and decolletage crepiness. (6) Magnitude — it is ‘overall rejuvenation,’ not ‘dramatic local change’: results peak 4-8 weeks after the course; skin analyzers can quantify elasticity and hydration gains; visually it is a gradual ‘better complexion, firmer skin, a few years younger’ change, natural and understated. (7) When you feel it — changes begin 2-4 weeks after the first session, with the fullest effect after both sessions.
How is the Profhilo course done? How many sessions? Does it hurt?
Course and experience: (1) Standard course — 2 injections, 4 weeks apart; maintenance single sessions about every 6 months. The two sessions stack: the first initiates collagen renewal, the second reinforces it. (2) Method — the official 5-point BAP technique: 5 fixed points per cheek (pre-auricular, below the cheekbone, mid-cheek, etc.), 10 injections total, about 0.2ml slowly injected subcutaneously each. (3) Pain — subcutaneous superficial injections; with topical cream most rate 3-4/10; a pressure feeling during injection, 5-10 seconds per point, about 10 minutes total. (4) Post-injection look — small papules at injection points (like mosquito bites) are normal while the HA has not yet spread, absorbing within 2-3 days — schedule away from major events. (5) Recovery — no makeup or strenuous exercise for 24 hours; after the papule phase, completely traceless. (6) Neck course — the same 5-point approach (neck version), similar process.
Is Profhilo safe? What are the side effects?
Safety: (1) Purity — Profhilo contains no chemical cross-linker (BDDE), made by patented thermal stabilization with extremely high biocompatibility; a legitimate globally marketed product (EU CE mark, Korean MFDS approval) used for years. (2) Injection design — the BAP points are anatomically validated to avoid major facial nerves, vessels, and expression muscles; safety confirmed in large-scale clinical use. (3) Common side effects — injection-point papules (absorbing in 2-3 days), mild redness (within 24 hours), small bruises in a few (3-5 days), transient fullness — all mild and self-limiting. (4) Rare risks — as with any injection, infection and allergy (HA allergy is extremely rare) are theoretical; sterile technique and authentic products are the prevention. (5) Contraindications — pregnancy and breastfeeding, active infection at the injection zone, acute autoimmune disease, and HA allergy are not advised. (6) Rappoel’s promise — authentic original Profhilo only (verifiable), fully sterile procedures, and post-treatment follow-up.
How long does Profhilo last? Do I need to keep injecting forever?
Duration and maintenance: (1) Duration — after the standard 2-session course, results last about 6 months (varying with metabolism and age); the effect fades slowly rather than falling off a cliff. (2) Maintenance rhythm — a single maintenance session about every 6 months (one fewer than the initial course) works like ‘interest on a collagen deposit,’ sustaining the youthful state. (3) If you stop — nothing worsens: collagen metabolism simply returns to its natural pace and skin returns to ‘normal for your age,’ though the collagen Profhilo built leaves the baseline slightly better than never-treated. (4) Cumulative effect — long-term regular users show measurable gains in dermal thickness and elasticity, and some can gradually extend intervals. (5) Combined maintenance — alternating with Thermage FLX (Thermage yearly, Profhilo half-yearly) is a popular efficient anti-aging combo. (6) Rappoel builds a skin-analysis record for you, tracking results with data and planning the most economical maintenance rhythm.
Who is suitable for Profhilo? Who is not?
Suitable: (1) ages 30-55 with early laxity and declining elasticity — the core group; (2) dull, rough skin in a ‘skincare plateau’ (nothing seems to work); (3) natural-look seekers who dislike filler puffs; (4) neck and decolletage fine lines and laxity — zones most treatments miss; (5) those who completed fillers and want overall skin-quality elevation; (6) post-weight-loss or postpartum laxity; (7) those avoiding device pain (Profhilo is comfortable). Unsuitable or cautious: (1) pregnancy and breastfeeding (postpone); (2) active infection or cystic acne flares at the zone (treat first); (3) HA allergy (extremely rare); (4) acute autoimmune disease; (5) severe skin laxity and descent — Profhilo’s improvement is limited; evaluate devices or surgical lifting; (6) those expecting ‘instant transformation’ — Profhilo regenerates gradually (2-4 weeks onset), not an immediate filler effect; (7) minors.
How soon does Profhilo work? What is the downtime?
Timeline and recovery: (1) Onset — 2-4 weeks after the first session: hydration and dewy glow (HA water-binding); 4-8 weeks (after session two): collagen matures and firmness clearly rises. (2) Peak — 4-8 weeks after completing both sessions, with measurable elasticity gains. (3) Downtime — day one: small papules at points and mild redness; days 2-3: papules absorb and spread; afterward completely traceless. Social impact is minimal — most return to work the next day (hair can cover cheek points; simply avoid injecting within 3 days before major events). (4) Aftercare — no makeup, strenuous exercise, or heat (sauna) for 24 hours; no massage needed (Profhilo is designed to spread on its own); extra moisturizing and sun protection optimize results. (5) Intervals with other treatments — fillers can be same-day in different zones; lasers 1-2 weeks apart; Thermage 2-4 weeks before or after. (6) Note — collagen renewal takes time; avoid aggressive dieting within a month of the course (it starves collagen synthesis of raw materials).
How much does Profhilo cost? Why is it pricier than regular skin boosters?
Cost explained: (1) Price structure — Profhilo is IBSA’s patented Italian original (consistent global quality) with the industry’s highest 128mg concentration; raw material cost alone exceeds typical injectables, plus the certified BAP technique — pricing above regular skin boosters is normal. (2) Versus skin boosters — boosters are cheaper per session but need frequent monthly repeats; Profhilo’s 2-session course lasts about 6 months, narrowing the annualized cost gap while delivering collagen renewal rather than mere hydration. (3) Versus Thermage — Thermage costs more per session; mechanisms differ (RF heat vs biological stimulation), and budget permitting they combine well. (4) Rappoel’s pricing — reasonable and transparent, guaranteed authentic (package and lot verifiable on site), course pricing quoted after consultation with no hidden fees. (5) Course offers — the initial 2-session course usually carries a package price, with loyalty plans for long-term maintenance guests. (6) For specific pricing, book a free consultation and have the most suitable skin-quality combination assessed.
Can Profhilo be combined with Thermage or Rejuran? How should I schedule them?
Combination planning: (1) Profhilo plus Thermage FLX — the premium anti-aging combo: Thermage contracts and stimulates deep collagen with RF heat while Profhilo activates dermal renewal biologically — ‘device plus injectable’ twin engines. Suggested order: Thermage first (deep stimulation), Profhilo 2-4 weeks later (dermal repair and renewal) for multiplied effects. (2) Profhilo plus Rejuran — the ‘remodel plus repair’ combo: Profhilo firms via collagen; Rejuran (salmon DNA) repairs damaged skin and refines texture; alternate 2-4 weeks apart, roughly monthly each. (3) Profhilo plus HA filler — filler treats local hollows (tear troughs, nasolabial) while Profhilo elevates overall quality; order is flexible (same day, different zones). (4) Profhilo plus botox — fully compatible; botox handles dynamic lines while Profhilo improves overall laxity and dullness; same day possible. (5) General scheduling — separate devices (Thermage/laser) from injectables by 1-2 weeks; injectables spaced per physician assessment. (6) Rappoel provides personalized anti-aging combination assessment, sequencing treatments by skin-age testing for maximum efficiency.
Will Profhilo give me a ‘pillowy filler face’? Will people notice?
Naturalness explained: (1) No filler volume — Profhilo diffuses through tissue without creating local volume — so there is no post-filler ‘puffy feel’ or ‘filler face’; the face does not widen or enlarge. (2) Short-term look — the only visible trace is injection-point papules (2-3 days), located on the outer cheek and pre-auricular area (the BAP points), naturally covered by hair; after they fade, nothing remains. (3) Long-term look — the result is firmer, brighter skin with softened fine lines — others perceive ‘better complexion,’ ‘great skin lately,’ or ‘did you go on vacation?’ rather than ‘she had work done.’ (4) Selfie comparison — same-lighting before-and-after selfies show the glow and firmness gains most clearly to you; this is why Profhilo is popular with natural-look clients (men, professionals, low-key maintainers). (5) Division of labor with filler — if you need local volume (cheeks, chin), do filler; if you need overall skin rejuvenation, do Profhilo — different purposes, no either/or. (6) Rappoel values ‘invisible natural youth’ and designs every treatment around overall harmony.
Loose, dull skin in a skincare plateau? Rappoel Profhilo — 2 sessions to switch on full-face collagen renewal!
📍 77, Seocho-daero, Seocho-gu, Seoul, South Korea
🕐 Mon–Fri 10:00–19:00 · Sat 10:00–17:00
💬 WeChat Main: rappoelkr | WeChat Backup: rappoelkr2 | LINE: rappoelkr
Scan to connect with us
WeChat (Main)
WeChat (Backup)
LINE