They say hands are the second face — and it’s true. The backs of the hands have thin skin, minimal subcutaneous fat, and are constantly exposed to sunlight, making them one of the first areas to show aging. Yet most people focus on facial anti-aging while neglecting their hands. Rappoel Dermatology Clinic in Seoul offers Rejuran PDRN hand rejuvenation, using deep-sea salmon DNA extract to stimulate collagen regeneration and address the root causes of hand aging.

Common Signs of Hand Aging

• Rough, dry texture: Few sebaceous glands mean faster moisture loss
• Deepening fine lines: Wrinkles become more obvious around knuckles and on the dorsum
• Prominent veins and tendons: Thinning subcutaneous tissue makes veins and tendons more visible
• Hyperpigmentation: Years of sun exposure lead to dark spots and uneven tone
• Loss of elasticity: Collagen depletion causes loose, crepey skin

How Rejuran Hand Rejuvenation Works

Rejuran’s active ingredient — PDRN (Polydeoxyribonucleotide) — is extracted from Korean deep-sea salmon DNA, molecularly very similar to human DNA. When injected into the dermal layer of the hands, PDRN activates fibroblast cells and promotes new collagen synthesis. The key effects include:

• Thickening and firming subcutaneous tissue from within
• Improving skin tone and luminosity via microcirculation boost
• Smoothing fine lines through collagen regeneration
• Long-lasting hydration — improving skin’s water retention ability
• Anti-inflammatory repair of damaged cells

Rappoel Procedure

Hand Rejuran requires even distribution and precise technique. The director uses a multi-point micro-injection method to deliver Rejuran uniformly across both hands, ensuring every area receives PDRN. The shallow-depth injection is minimally painful and requires no special anesthesia for most patients.

Recommended Treatment Plan

• Session 1: Establish PDRN foundation and initiate collagen regeneration
• Session 2 (1 month later): Consolidate effects, continued collagen production
• Session 3 (3 months later): Stabilize optimal results — skin is noticeably thicker and smoother
• Maintenance: Once every 6–12 months

Post-Treatment Care

• Avoid washing hands for 24 hours
• No vigorous rubbing of the dorsum
• Apply SPF 50 sunscreen to protect treated skin
• Use hand moisturizer daily to support hydration

Rappoel Clinic: 5F, 24-gil, Seocho-daero 77, Seocho-gu, Seoul — 3 min from Gangnam Station Exit 10.

Frequently Asked Questions

Book Rejuran Hand Rejuvenation at Rappoel Seoul

📍 77, Seocho-daero, Seocho-gu, Seoul, South Korea

🕐 Mon–Fri 10:00–19:00 · Sat 10:00–17:00

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