Enlarged pores are among the most common skin concerns — not a disease but significantly affecting skin texture and appearance. Pores are the skin-surface openings of hair follicles — each containing a hair and associated sebaceous gland. Visual pore size depends on three factors: (1) Sebaceous gland activity — the T-zone (forehead, nose, nasal sides) with active sebum production has more visible pores. (2) Peripore skin support — when collagen and elastin around pores decrease, pore walls lose support and expand, making pores appear larger. (3) Skin hydration — pores are more visible when skin is dehydrated. Causes of enlarged pores include: (1) Genetics — oily skin types naturally have larger pores. (2) Aging — collagen loss reduces peripore support. (3) UV damage — photoaging accelerates collagen degradation. (4) Improper skincare — over-cleansing disrupts the skin barrier; squeezing comedones stretches pores. (5) Hormonal changes — elevated androgens stimulate sebum production. Rappoel Dermatology near Gangnam Station, Seoul, uses Rejuran PDRN — through dermal micro-injection to repair damaged skin from the root, improving enlarged pores and restoring smooth, refined skin texture.
Technical Principles of Rejuran PDRN Pore Repair
- PDRN promotes dermal repair and regeneration: Rejuran’s core ingredient is PDRN (Polydeoxyribonucleotide) — DNA fragments extracted from salmon testes. PDRN activates adenosine A2A receptors promoting fibroblast proliferation and collagen synthesis — clinical studies show 20-30% increase in dermal collagen density after PDRN injection, with increased elastic fibers enhancing peripore support
- Microneedle injection for precise dermal delivery: Rejuran uses ultra-fine 32G needles for uniform facial micro-injection — delivering PDRN precisely to the dermal papillary and reticular layers (where pores reside). Unlike topical skincare that only reaches the epidermis, micro-injection ensures PDRN acts directly on the dermis surrounding pores
- Triple mechanism for pore reduction: (1) Collagen proliferation enhances pore wall support — increased peripore collagen density tightens pore walls, visually shrinking pores. (2) Barrier repair improves hydration — PDRN repairs damaged dermal matrix, enhancing skin’s water-retention capacity, making pores less visible through improved hydration. (3) Anti-inflammatory effect reduces sebaceous stimulation — PDRN’s anti-inflammatory properties reduce follicular inflammation, indirectly decreasing excessive sebum production
- High safety with no rejection risk: PDRN-derived DNA fragments are highly homologous to human DNA — no immune rejection. Salmon DNA shares approximately 95% similarity with human DNA, purified for safe human injection
- Suitable for long-term repeated treatment: Rejuran is a biological repair treatment — unlike Botox with resistance risk, it can be used long-term for continuous skin quality improvement
Rejuran Treatment Strategies for Different Pore Types
- T-zone oily pores: Enlarged pores in forehead, nose, and nasal sides with active sebum production. Strategy: full-face Rejuran micro-injection + T-zone enhanced injection. Each T-zone area receives an additional 0.5ml. Combined with oil-control skincare, visible pore reduction in 4 weeks
- Full-face aging pores: Uniformly enlarged pores across the face with skin laxity and fine lines. Strategy: 3-5 full-face Rejuran sessions, 3-4 weeks apart. 2ml per session, uniform micro-injection. Combined with Thermage FLX for enhanced tightening
- Cheek pores: Enlarged cheek pores with normal T-zone, usually related to UV damage and dryness. Strategy: Rejuran focused on cheek area, 1-2ml concentrated per session. Combined with strict sun protection and moisturizing
- Ice-pick acne scar pores: Pores transformed into deep, pointed ice-pick scars from acne damage. Strategy: 3-5 Rejuran sessions for dermal repair, but deep scars may need combined fractional laser. Rejuran serves as post-laser repair adjunct
- Mixed pores: T-zone oily pores + cheek aging pores. Strategy: full-face Rejuran with T-zone enhanced volume. 2ml full-face + 0.5ml T-zone per session
Rappoel Rejuran Pore Repair Treatment Protocol
- Skin assessment and plan design (15 min): Use skin analyzer to evaluate pore type and distribution → assess sebum production level → evaluate skin hydration → establish injection plan (volume, focus areas, session count)
- Topical anesthesia (20 min): Facial cleansing → apply lidocaine topical anesthetic → cover with plastic film → wait 20 minutes → remove anesthetic
- Rejuran micro-injection (20-30 min): 32G ultra-fine needle → uniform micro-injection points across face (0.5-1cm spacing) → 0.01-0.02ml Rejuran per point → enhanced density in focus areas (T-zone/pore-heavy areas) → total 2ml full-face
- Post-treatment care and soothing (15 min): Rejuran recovery mask for soothing → apply repair cream and sunscreen → post-care instructions (no makeup for 24 hours, no swimming, no sauna, enhanced sun protection and moisturizing) → schedule 3-4 week follow-up
The entire Rejuran PDRN pore repair procedure takes about 60-70 minutes. Microneedle marks fade in 2-3 days, pore reduction and skin texture improvement begin at 2-4 weeks, optimal results after 3-5 sessions. Located 3 minutes from Gangnam Station Exit 10, with seamless English and Chinese consultation.
Frequently Asked Questions
How many Rejuran sessions are needed to see pore improvement?
Rejuran pore improvement timeline: (1) 1-2 weeks after first session — skin hydration improves, pores appear less visible from moisturizing effect (about 10-15% improvement). (2) 3-4 weeks after first session — PDRN-promoted collagen begins proliferating, peripore support enhances, pores visually shrink 20-30%. (3) After 3 sessions (about 3 months) — cumulative 40-50% improvement, visibly smaller pores, refined skin texture. (4) After 5 sessions (about 5 months) — cumulative 50-60% improvement, optimal results. Maintenance: one session every 3-4 months after initial course. Factors: pore type (oily pores improve faster than aging pores), age (younger skin has stronger repair capacity), sun protection and skincare habits.
What is the difference between Rejuran and skin booster (mesotherapy) for pores?
Both are micro-injection treatments but with different core ingredients and mechanisms: (1) Rejuran PDRN — core ingredient is polydeoxyribonucleotide, primarily promoting dermal fibroblast proliferation and collagen synthesis to repair pore-surrounding skin structure from the root. Suitable for: aging pores, poor skin quality, dermal repair needs. (2) Skin booster — core ingredient is hyaluronic acid, primarily providing intense hydration to plump skin, making pores visually smaller through skin fullness. Suitable for: dry pores, dehydrated skin, instant hydration needs. (3) Combined — Rejuran + skin booster can alternate within the same course: Rejuran repairs dermal structure, skin booster provides hydration, synergistic for optimal results. Rappoel can mix Rejuran and skin booster in the same session (per physician assessment), achieving both structural repair and deep hydration.
Is Rejuran injection painful? How long is the recovery?
Rejuran micro-injection pain and recovery: (1) Pain — very mild after topical anesthetic, similar to rubber band snaps. 32G ultra-fine needles minimize puncture pain. Most patients tolerate the full treatment. For especially pain-sensitive patients, stronger anesthetic or ice compress can be used. (2) Recovery — uniform small red dots and mild swelling (needle reactions) appear post-injection, typically resolving in 24-48 hours. Makeup can be applied the next day (to cover redness), with normal appearance by day 3. (3) Post-care — no makeup for 24 hours, cleanse with water only (no cleanser), no swimming or sauna, strict sun protection (SPF50+). Use repair skincare for 1 week to help microneedle channel healing. Rappoel provides post-treatment recovery mask and cream to accelerate healing.
How long do Rejuran pore results last?
Rejuran pore improvement lasts 6-12 months, depending on: (1) Session count — completing 3-5 initial sessions provides more lasting results (PDRN-promoted collagen proliferation is cumulative). (2) Pore type — oily pores without sebum control last shorter (4-6 months), aging pores last longer (8-12 months). (3) Age — younger skin with slower collagen metabolism maintains results longer; those over 40 may need more frequent maintenance. (4) Lifestyle — good sun protection, regular sleep, and proper skincare extend results. Rappoel maintenance protocol: initial course 3-5 sessions (3-4 weeks apart), then maintenance every 3-4 months. Long-term maintenance keeps pores at their best while continuously improving overall skin quality. Rejuran does not cause resistance and is safe for long-term use.
Can Rejuran be combined with fractional laser?
Yes, with complementary effects — Rejuran + fractional laser is the golden combination for comprehensive pore + acne scar treatment: (1) Complementary effects — fractional laser creates microthermal zones (MTZ) stimulating skin remodeling and collagen regeneration, effective for deep scars and large pores. Rejuran’s PDRN promotes fibroblast proliferation to accelerate post-laser recovery while enhancing collagen synthesis. Synergy — laser provides physical stimulation to initiate repair, Rejuran provides bioactive ingredients to accelerate it. (2) Time interval — not recommended on the same day (avoiding over-stimulation). Plan A: fractional laser first, start Rejuran repair series 2 weeks later (3 sessions, 3-4 weeks apart). Plan B: Rejuran 3 sessions first to build dermal foundation, fractional laser 4 weeks later, then 1-2 additional Rejuran sessions 2 weeks post-laser. (3) Suitable for — those with enlarged pores plus acne scars, poor skin quality, slow recovery. Rappoel physicians design personalized combined plans.
Enlarged pores making skin rough? Rappoel Rejuran PDRN pore repair — refined skin in 4 weeks!
📍 77, Seocho-daero, Seocho-gu, Seoul, South Korea
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