Excessive Underarm Sweating? Seoul Rappoel’s Coretox Micro-Injection Treatment for Hyperhidrosis



Hyperhidrosis is a common condition of sweat gland overactivity, causing persistent and excessive sweating in the underarms, palms, or soles — even without exercise or heat. This is not simply sweating easily — it soaks through clothing, causes social embarrassment, and impacts professional image and quality of life. Seoul Rappoel Clinic offers Coretox botulinum toxin micro-injection therapy for hyperhidrosis, blocking the nerve signals to sweat glands at the source. A single treatment provides approximately 6 months of dry comfort.

Diagnostic Criteria for Hyperhidrosis

You may have primary hyperhidrosis if you meet at least two of the following:

  • Sweating is disproportionate to ambient temperature and physical activity, occurring without obvious triggers
  • Sweating is bilateral and symmetrical (e.g., both underarms soak clothing simultaneously)
  • Troublesome excessive sweating occurs at least 1–2 times per week
  • Onset is typically before age 25
  • Sweating does not occur during sleep (nocturnal sweating may suggest other underlying medical conditions)
  • A clear genetic tendency (family members often also have hyperhidrosis)

How Coretox Stops Excessive Sweating

  • Blocks sweat gland nerve signals: Coretox selectively inhibits acetylcholine release from sympathetic nerve terminals supplying eccrine sweat glands
  • Reduced sweat gland activity: Without nerve signaling, sweat glands drastically reduce secretion
  • Localized effect only: The effect is confined to the injected area — the rest of the body continues to sweat normally for thermoregulation
  • No gland damage: The effect is functional (inhibition, not destruction); sweat gland function recovers after the treatment wears off

Rappoel’s Hyperhidrosis Protocol

  • Pre-treatment iodine-starch test: Iodine and starch applied to the underarm to map the active sweating areas and severity
  • Grid-marked injection: Injection grid marked based on iodine-starch results to ensure complete coverage
  • Ultra-fine intradermal injection: Coretox delivered into the dermis with 32G ultra-fine needles
  • Bilateral symmetrical treatment: Equal dosing for both underarms; typically approximately 100 units total
  • 10-minute procedure: The entire injection process takes about 10 minutes

Treatment Timeline

  • 3–5 days: Noticeable reduction in sweating begins
  • 1–2 weeks: Maximum dryness achieved
  • Duration: Approximately 6–8 months before gradual return
  • Maintenance: 1–2 treatments per year maintain dryness

Suitable treatment areas: underarms (most common), palms, soles, frontal hairline. Rappoel Clinic: 5F, 24 Seocho-daero 77-gil, Seocho-gu, Seoul.

Frequently Asked Questions

Will hyperhidrosis treatment affect whole-body sweating?
No. Coretox only blocks sweat gland signals in the injected area (e.g., underarms). The rest of your body’s thermoregulatory sweating remains completely normal — exercise and hot-weather cooling are unaffected.
Are the injections painful?
With 32G ultra-fine needles and topical anesthetic, most patients tolerate it easily. The underarm area has moderate sensitivity, and most find it very manageable. The entire procedure takes about 10 minutes.
When can I shower after treatment?
We recommend avoiding scrubbing the underarm area and hot showers for 24 hours. You can resume normal activities and fly the same day.
Does this affect body odor?
Hyperhidrosis treatment primarily targets eccrine glands — responsible for profuse watery sweat. The effect on apocrine glands — the main source of body odor — is limited. If body odor rather than sweat volume is your main concern, alternative treatments may need evaluation.
How often do I need repeat treatments?
Sweating gradually returns to pre-treatment levels in approximately 6–8 months. One to two treatments per year maintain dryness. Some individuals experience progressively longer-lasting effects with repeated treatments.

Book a Coretox Hyperhidrosis Treatment

📍 77, Seocho-daero, Seocho-gu, Seoul, South Korea

🕐 Mon–Fri 10:00–19:00 · Sat 10:00–17:00

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