Hyperhidrosis is a common condition of sweat gland overactivity, causing persistent and excessive sweating in the underarms, palms, or soles — even without exercise or heat. This is not simply sweating easily — it soaks through clothing, causes social embarrassment, and impacts professional image and quality of life. Seoul Rappoel Clinic offers Coretox botulinum toxin micro-injection therapy for hyperhidrosis, blocking the nerve signals to sweat glands at the source. A single treatment provides approximately 6 months of dry comfort.
Diagnostic Criteria for Hyperhidrosis
You may have primary hyperhidrosis if you meet at least two of the following:
- Sweating is disproportionate to ambient temperature and physical activity, occurring without obvious triggers
- Sweating is bilateral and symmetrical (e.g., both underarms soak clothing simultaneously)
- Troublesome excessive sweating occurs at least 1–2 times per week
- Onset is typically before age 25
- Sweating does not occur during sleep (nocturnal sweating may suggest other underlying medical conditions)
- A clear genetic tendency (family members often also have hyperhidrosis)
How Coretox Stops Excessive Sweating
- Blocks sweat gland nerve signals: Coretox selectively inhibits acetylcholine release from sympathetic nerve terminals supplying eccrine sweat glands
- Reduced sweat gland activity: Without nerve signaling, sweat glands drastically reduce secretion
- Localized effect only: The effect is confined to the injected area — the rest of the body continues to sweat normally for thermoregulation
- No gland damage: The effect is functional (inhibition, not destruction); sweat gland function recovers after the treatment wears off
Rappoel’s Hyperhidrosis Protocol
- Pre-treatment iodine-starch test: Iodine and starch applied to the underarm to map the active sweating areas and severity
- Grid-marked injection: Injection grid marked based on iodine-starch results to ensure complete coverage
- Ultra-fine intradermal injection: Coretox delivered into the dermis with 32G ultra-fine needles
- Bilateral symmetrical treatment: Equal dosing for both underarms; typically approximately 100 units total
- 10-minute procedure: The entire injection process takes about 10 minutes
Treatment Timeline
- 3–5 days: Noticeable reduction in sweating begins
- 1–2 weeks: Maximum dryness achieved
- Duration: Approximately 6–8 months before gradual return
- Maintenance: 1–2 treatments per year maintain dryness
Suitable treatment areas: underarms (most common), palms, soles, frontal hairline. Rappoel Clinic: 5F, 24 Seocho-daero 77-gil, Seocho-gu, Seoul.
Frequently Asked Questions
Book a Coretox Hyperhidrosis Treatment
📍 77, Seocho-daero, Seocho-gu, Seoul, South Korea
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