Coretox Botox for Crow’s Feet and Eye Area Wrinkles in Seoul: Precise Treatment at Rappoel Dermatology Gangnam<\/title><br \/>\n<meta name=\"description\" content=\"Crow's feet aging your smile and under-eye lines ruining your makeup? Rappoel Dermatology uses Korea's Coretox botulinum toxin \u2014 precisely relaxing the orbicularis oculi muscle for visible results in 3 days\">\n<link rel=\"alternate\" hreflang=\"en\" href=\"https:\/\/rappoel-clinic.com\/coretox-crows-feet-botox-en\/\" \/>\n<link rel=\"alternate\" hreflang=\"zh-TW\" href=\"https:\/\/rappoel-clinic.com\/coretox-crows-feet-botox-zh\/\" \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"MedicalClinic\", \"@id\": \"https:\/\/rappoel-clinic.com\/#clinic\", \"name\": \"Rappoel Dermatology Clinic\", \"alternateName\": [\"Rappoel \u76ae\u819a\u79d1\", \"\ub77c\ud3ec\uc5d8 \ud53c\ubd80\uacfc\"], \"url\": \"https:\/\/rappoel-clinic.com\", \"address\": {\"@type\": \"PostalAddress\", \"streetAddress\": \"77, Seocho-daero\", \"addressLocality\": \"Seocho-gu\", \"addressRegion\": \"Seoul\", \"postalCode\": \"06609\", \"addressCountry\": \"KR\"}, \"geo\": {\"@type\": \"GeoCoordinates\", \"latitude\": 37.4926, \"longitude\": 127.0175}, \"telephone\": \"+82-2-XXXX-XXXX\", \"openingHours\": [\"Mo-Fr 10:00-19:00\", \"Sa 10:00-17:00\"], \"medicalSpecialty\": \"Dermatology\", \"availableService\": [{\"@type\": \"MedicalProcedure\", \"name\": \"Thread Lift (Aptos)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Hyaluronic Acid Filler\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Botulinum Toxin (Botox)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Ultherapy \/ HIFU\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Skin Booster (Juvelook \/ Exosomes)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Laser Skin Treatment\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Onda Coolwaves Body Contouring\"}], \"sameAs\": [\"https:\/\/www.instagram.com\/rappoel_official\"]}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"Article\", \"headline\": \"Coretox Botox for Crow's Feet and Eye Area Wrinkles in Seoul: Precise Treatment at Rappoel Dermatology Gangnam\", \"description\": \"Crow's feet aging your smile and under-eye lines ruining your makeup? Rappoel Dermatology uses Korea's Coretox botulinum toxin \u2014 precisely relaxing the orbicularis oculi muscle for visible results in 3 days\", \"inLanguage\": \"en\", \"author\": {\"@type\": \"Organization\", \"name\": \"Rappoel Dermatology Clinic\"}, \"publisher\": {\"@type\": \"Organization\", \"name\": \"Rappoel Dermatology Clinic\", \"logo\": {\"@type\": \"ImageObject\", \"url\": \"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/favicon-512.png\"}}, \"about\": {\"@id\": \"https:\/\/rappoel-clinic.com\/#clinic\"}}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"Will periocular Botox affect my facial expressions? Will my smile look unnatural?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"This is the most common concern, but correct injection does not affect natural expression. The keys are: (1) Dosage control \u2014 6-12 units Coretox per side for crow's feet is the safe effective range. Rappoel's philosophy is relaxation, not complete freezing \u2014 reducing 70-80% of crow's feet contraction while preserving 20-30% natural expression. (2) Injection depth \u2014 injected in the superficial subcutaneous layer (superficial orbicularis fibers), not deep enough to reach the zygomaticus major, avoiding smile muscle interference. (3) Injection points \u2014 2-3 points per side distributed evenly in the safe zone 1-1.5cm lateral to the canthus, not near the eye corner or infraorbital margin. (4) Dynamic assessment \u2014 the physician has the patient smile repeatedly after injection to confirm natural results. Unnatural results typically occur from excessive dosage (over 15 units\/side) or too-deep injection spreading to the zygomaticus \u2014 completely avoidable by experienced physicians. 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(4) Preservatives \u2014 Coretox contains no animal-derived proteins or human serum albumin, lower allergy risk. (5) Origin \u2014 Coretox is domestically produced in Korea with stable supply. Rappoel selects based on patient needs \u2014 Coretox recommended for those needing fast results or experiencing diminished Botox effect; Botox also available for first-time patients or those accustomed to it. Both last similarly (4-6 months).\"}}, {\"@type\": \"Question\", \"name\": \"Can under-eye lines also be treated with Botox? Is it the same as crow's feet?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Under-eye line Botox treatment is not identical to crow's feet and requires more caution: (1) Indication selection \u2014 under-eye lines are divided into dynamic (deepened by blinking and squinting) and static (present at rest). Botox only works on dynamic under-eye lines \u2014 static lines need combination treatments (e.g., PDRN injection, laser, filler). (2) Injection location \u2014 under-eye Botox is injected 1-2mm below the lash line in the infratarsal area, 1-2 points per side, 1-2 units per point (much lower dosage than crow's feet). (3) Higher risk \u2014 under-eye injection may cause ectropion, worsened eye bags, or aggravated dry eye. Rappoel physicians assess eyelid elasticity and eye bag status before injection \u2014 those with eyelid laxity or prominent eye bags are not candidates for under-eye injection. (4) Effect \u2014 under-eye line improvement is typically less pronounced than crow's feet (due to more complex etiology). Rappoel typically recommends combined crow's feet + under-eye injection, but with very low under-eye dosage (total 2-4 units) for safety.\"}}, {\"@type\": \"Question\", \"name\": \"How long does periocular Botox last? Will I develop resistance from repeated treatments?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Periocular Botox typically lasts 4-6 months \u2014 because the neuromuscular junction gradually regenerates new acetylcholine receptors restoring muscle contraction. Factors affecting duration: (1) Individual metabolic rate \u2014 faster metabolism means faster effect fade. (2) Muscle strength \u2014 stronger orbicularis oculi may need higher dosage and lose effect faster. (3) Injection technique \u2014 precise injection into target muscle lasts longer. Regarding resistance: long-term repeated Botox injections may produce neutralizing antibodies causing diminished effect \u2014 incidence approximately 1-5%. Coretox's high-purity formulation theoretically reduces antibody risk. Strategies to minimize resistance: (1) No boosters while effect persists (minimum 3-month intervals). (2) Use the lowest effective dose. (3) Switch toxin types if effect diminishes (type A to type B or different brand of type A). Rappoel records each patient's injection history, scientifically managing intervals and dosage.\"}}, {\"@type\": \"Question\", \"name\": \"Can periocular Botox be combined with other treatments? What are the contraindications?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Periocular Botox can be safely combined with multiple treatments: (1) Same-day \u2014 HA fillers (tear trough, nasolabial folds in different areas), PDRN injection (different facial areas), mesotherapy. As long as injections aren't stacked at the same point. (2) 1-2 weeks apart \u2014 laser treatments (fractional laser, IPL), do laser first and wait for skin recovery before Botox, or Botox first and wait for muscle stabilization before laser. (3) 2-4 weeks apart \u2014 thread lifting, recommend thread lift first and wait for swelling to subside before Botox, to avoid swelling affecting diffusion assessment. Contraindications: (1) Active periocular infection (stye, conjunctivitis). (2) Myasthenia gravis or Lambert-Eaton syndrome. (3) Pregnancy and breastfeeding. (4) Allergy to Botox components. (5) Ptosis or incomplete eyelid closure \u2014 caution with under-eye injection. Rappoel physicians take detailed medical history before injection to rule out contraindications.\"}}]}<\/script><\/p>\n<style>\n*{box-sizing:border-box;margin:0;padding:0}\nbody{font-family:'PingFang SC','Noto Sans KR',sans-serif;background:#fffcf7;color:#3d2e1e;line-height:1.8}\n.wrap{max-width:677px;margin:0 auto;padding:32px 20px 60px}\n.banner{background:#FFF8EC;text-align:center;padding:36px 20px 28px;margin-bottom:36px;border-bottom:1px solid #e8d5c0}\n.banner-tag{font-size:11px;letter-spacing:3px;color:#8B7355;text-transform:uppercase;margin-bottom:12px}\n.banner h1{font-size:24px;color:#3d2e1e;line-height:1.4;margin-bottom:12px}\n.banner .sub{font-size:13px;color:#6b5240;line-height:1.7}\nh2{font-size:19px;color:#3d2e1e;margin:32px 0 14px;padding-bottom:8px;border-bottom:1px solid #e8d5c0}\nh3{font-size:16px;color:#3d2e1e;margin:22px 0 10px}\np{font-size:15px;color:#555;line-height:1.9;margin-bottom:14px}\n.highlight{background:#fff;border:1px solid #f0e8dc;border-left:3px solid #D4A574;padding:16px 20px;margin:22px 0;border-radius:0 6px 6px 0}\n.highlight p{margin:0;font-size:14px;color:#6b5240}\n.card{background:#F5E6C8;border:1px solid #e8d5c0;border-radius:8px;padding:18px 22px;margin:16px 0}\n.card-title{font-size:13px;font-weight:700;color:#3d2e1e;margin-bottom:6px}\n.card p{font-size:14px;margin:0}\n.faq-item{margin:14px 0;border-bottom:1px solid #f0e8dc;padding-bottom:14px}\n.faq-q{font-weight:700;color:#3d2e1e;font-size:15px;margin-bottom:6px}\n.faq-a{font-size:14px;color:#555;line-height:1.8}\n.cta{background:#F5E6C8;text-align:center;padding:32px 20px;margin-top:40px;border-radius:8px}\n.cta h3{font-size:17px;color:#3d2e1e;margin-bottom:8px}\n.cta p{font-size:13px;color:#6b5240;margin-bottom:4px}\nimg{max-width:100%;height:auto;display:block;margin:20px auto;border-radius:6px}\nul,ol{padding-left:22px;margin-bottom:14px}\nli{font-size:15px;color:#555;line-height:1.9;margin-bottom:4px}\n.schema-block{display:none}\n@media(max-width:600px){.wrap{padding:20px 14px 40px}.banner h1{font-size:20px}}\n<\/style>\n<p><\/head><br \/>\n<body><\/p>\n<div class=\"wrap\">\n<div class=\"banner\">\n<div class=\"banner-tag\">Botox<\/div>\n<h1>Coretox Botox for Crow’s Feet and Eye Area Wrinkles in Seoul: Precise Treatment at Rappoel Dermatology Gangnam<\/h1>\n<div class=\"sub\">Crow’s feet aging your smile and under-eye lines ruining your makeup? Rappoel Dermatology uses Korea’s Coretox botulinum toxin \u2014 precisely relaxing the orbicularis oculi muscle for visible results in 3 days<\/div>\n<\/p><\/div>\n<p>The eye area is the most fragile and age-revealing region of the face \u2014 eye skin is only 0.3-0.5mm thick (the thinnest on the face), with minimal sebaceous and sweat glands leading to poor natural hydration, combined with tens of thousands of daily blinks and rich expression muscle activity, making the eyes the first area to develop wrinkles. Periocular wrinkles are categorized into three types: (1) Crow’s feet \u2014 radiating lines extending from the outer eye corner, deepened by smiling, caused by contraction of the lateral orbicularis oculi. (2) Under-eye lines \u2014 fine horizontal lines in the under-eye area, related to orbicularis oculi contraction and skin dryness. (3) Eyelid lines \u2014 horizontal lines on the upper eyelid. Additionally, glabellar lines (between brows) and forehead lines typically appear alongside periocular wrinkles. Causes include hyperactive orbicularis oculi (dynamic wrinkles), photoaging (UVA destroying dermal collagen), skin dehydration, eye-rubbing habits, and repeated friction from eye makeup. Rappoel Dermatology near Gangnam Station, Seoul, uses Korea’s Coretox botulinum toxin \u2014 precisely injecting the lateral orbicularis oculi to safely and effectively eliminate periocular dynamic wrinkles and restore bright, youthful eyes.<\/p>\n<h2>Technical Advantages of Coretox Botulinum Toxin<\/h2>\n<ul>\n<li><strong>Korean-origin higher purity:<\/strong> Coretox is a 150kDa high-purity botulinum toxin type A developed by Daewoong Pharmaceutical \u2014 same type A as Botox (Allergan) but with different manufacturing processes. Coretox uses a unique purification process removing unnecessary complex proteins, theoretically reducing antibody formation and resistance risk \u2014 meaning for patients requiring long-term repeated injections, Coretox may maintain more consistent results over time<\/li>\n<li><strong>Faster onset (3-day results):<\/strong> Coretox clinical data shows average onset of 2-3 days, faster than traditional Botox (5-7 days) \u2014 beneficial for patients needing quick results (e.g., pre-event treatment)<\/li>\n<li><strong>Precise diffusion control:<\/strong> Coretox’s molecular properties result in smaller post-injection diffusion \u2014 particularly important in delicate areas like the periocular region, preventing toxin spread to non-target muscles (e.g., spreading to zygomaticus major causing smile asymmetry)<\/li>\n<li><strong>Preservative-free:<\/strong> Coretox formulation contains no animal-derived proteins or human serum albumin \u2014 reducing allergic reaction risk, safer for sensitive patients<\/li>\n<li><strong>Stable Korean domestic supply:<\/strong> Rappoel is located in Seoul, Korea \u2014 Coretox as a domestic product has stable supply without occasional import supply chain disruptions<\/li>\n<\/ul>\n<h2>Detailed Anatomy and Safety for Periocular Botox Injection<\/h2>\n<ul>\n<li><strong>Precise targeting of lateral orbicularis oculi:<\/strong> The treatment target for crow’s feet is the lateral orbicularis oculi (muscle fibers lateral to the outer eye corner). Injection must be 1-1.5cm lateral to the lateral canthus \u2014 too close may affect eyelid closure, too far yields insufficient effect<\/li>\n<li><strong>Avoiding zygomaticus major and risorius:<\/strong> The orbicularis oculi overlies the zygomaticus major \u2014 if toxin spreads to the zygomaticus, it causes midface drooping and smile asymmetry (crooked smile). Rappoel’s strategy: 2-3 injection points per side, 2-4 units Coretox per point, injected in the superficial subcutaneous layer (superficial orbicularis oculi), avoiding deep injection that could spread to the zygomaticus<\/li>\n<li><strong>Bony orbital rim landmark:<\/strong> All injection points are strictly lateral to the bony orbital rim \u2014 the physician palpates the orbital bone edge as a safety landmark, ensuring injections don’t enter the orbit and affect extraocular muscles<\/li>\n<li><strong>Asymmetry assessment:<\/strong> No face is perfectly symmetrical \u2014 left and right orbicularis oculi strength and wrinkle depth may differ. Rappoel physicians carefully mark bilateral wrinkle distribution before injection, adjusting dosage per side based on actual asymmetry<\/li>\n<li><strong>Avoiding over-treatment:<\/strong> Excessive orbicularis oculi injection can cause a fake smile appearance (eyes don’t move when smiling, looking unnatural) or worsened eye bags (orbicularis relaxation allows orbital fat bulging). Preserving some periocular expression is key to natural results<\/li>\n<\/ul>\n<h2>Rappoel Periocular Botox Injection Treatment Protocol<\/h2>\n<ol>\n<li><strong>Periocular assessment and plan design (10 min):<\/strong> Static and dynamic (smiling) evaluation of crow’s feet distribution and depth \u2192 assess under-eye lines \u2192 evaluate brow tail position and eyelid closure function \u2192 mark injection points (2-3 per side) \u2192 determine dosage (6-12 units Coretox per side)<\/li>\n<li><strong>Disinfection preparation (5 min):<\/strong> Facial cleansing \u2192 povidone-iodine periocular preparation \u2192 physician wears sterile gloves \u2192 30G ultra-fine insulin needle used for injection<\/li>\n<li><strong>Precise injection (5-8 min):<\/strong> 2-3 injection points per side \u2192 injection depth at superficial subcutaneous layer (superficial orbicularis oculi fibers) \u2192 2-4 units Coretox per point \u2192 gentle skin pinching during injection ensures superficial placement \u2192 immediate gentle pressure for hemostasis<\/li>\n<li><strong>Immediate assessment and guidance (5 min):<\/strong> Patient performs smiling and blinking to confirm onset of muscle relaxation \u2192 post-care instructions provided \u2192 2-week follow-up scheduled for effect evaluation<\/li>\n<\/ol>\n<p>The entire periocular Coretox injection takes only 15-20 minutes, with results visible in 3 days, full effect at 7-10 days, lasting 4-6 months. Located 3 minutes from Gangnam Station Exit 10, with seamless English and Chinese consultation.<\/p>\n<h2>Frequently Asked Questions<\/h2>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Will periocular Botox affect my facial expressions? Will my smile look unnatural?<\/div>\n<div class=\"faq-a\">This is the most common concern, but correct injection does not affect natural expression. The keys are: (1) Dosage control \u2014 6-12 units Coretox per side for crow’s feet is the safe effective range. Rappoel’s philosophy is relaxation, not complete freezing \u2014 reducing 70-80% of crow’s feet contraction while preserving 20-30% natural expression. (2) Injection depth \u2014 injected in the superficial subcutaneous layer (superficial orbicularis fibers), not deep enough to reach the zygomaticus major, avoiding smile muscle interference. (3) Injection points \u2014 2-3 points per side distributed evenly in the safe zone 1-1.5cm lateral to the canthus, not near the eye corner or infraorbital margin. (4) Dynamic assessment \u2014 the physician has the patient smile repeatedly after injection to confirm natural results. Unnatural results typically occur from excessive dosage (over 15 units\/side) or too-deep injection spreading to the zygomaticus \u2014 completely avoidable by experienced physicians. Rappoel’s goal is visibly reduced crow’s feet when smiling while maintaining lively, natural eyes.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">What is the difference between Coretox and Botox? Which is better?<\/div>\n<div class=\"faq-a\">Coretox and Botox are both botulinum toxin type A with the same core mechanism (blocking acetylcholine release to relax muscles), with these main differences: (1) Purity \u2014 Coretox is a 150kDa high-purity toxin with unnecessary complex proteins removed; Botox is a 900kDa complex containing auxiliary proteins. Higher purity theoretically reduces antibody formation risk \u2014 more beneficial for those needing long-term repeated injections. (2) Onset speed \u2014 Coretox averages 2-3 days onset, Botox typically 5-7 days. (3) Diffusion range \u2014 Coretox has relatively smaller diffusion, safer in delicate areas like the periocular region. (4) Preservatives \u2014 Coretox contains no animal-derived proteins or human serum albumin, lower allergy risk. (5) Origin \u2014 Coretox is domestically produced in Korea with stable supply. Rappoel selects based on patient needs \u2014 Coretox recommended for those needing fast results or experiencing diminished Botox effect; Botox also available for first-time patients or those accustomed to it. Both last similarly (4-6 months).<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Can under-eye lines also be treated with Botox? Is it the same as crow’s feet?<\/div>\n<div class=\"faq-a\">Under-eye line Botox treatment is not identical to crow’s feet and requires more caution: (1) Indication selection \u2014 under-eye lines are divided into dynamic (deepened by blinking and squinting) and static (present at rest). Botox only works on dynamic under-eye lines \u2014 static lines need combination treatments (e.g., PDRN injection, laser, filler). (2) Injection location \u2014 under-eye Botox is injected 1-2mm below the lash line in the infratarsal area, 1-2 points per side, 1-2 units per point (much lower dosage than crow’s feet). (3) Higher risk \u2014 under-eye injection may cause ectropion, worsened eye bags, or aggravated dry eye. Rappoel physicians assess eyelid elasticity and eye bag status before injection \u2014 those with eyelid laxity or prominent eye bags are not candidates for under-eye injection. (4) Effect \u2014 under-eye line improvement is typically less pronounced than crow’s feet (due to more complex etiology). Rappoel typically recommends combined crow’s feet + under-eye injection, but with very low under-eye dosage (total 2-4 units) for safety.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">How long does periocular Botox last? Will I develop resistance from repeated treatments?<\/div>\n<div class=\"faq-a\">Periocular Botox typically lasts 4-6 months \u2014 because the neuromuscular junction gradually regenerates new acetylcholine receptors restoring muscle contraction. Factors affecting duration: (1) Individual metabolic rate \u2014 faster metabolism means faster effect fade. (2) Muscle strength \u2014 stronger orbicularis oculi may need higher dosage and lose effect faster. (3) Injection technique \u2014 precise injection into target muscle lasts longer. Regarding resistance: long-term repeated Botox injections may produce neutralizing antibodies causing diminished effect \u2014 incidence approximately 1-5%. Coretox’s high-purity formulation theoretically reduces antibody risk. Strategies to minimize resistance: (1) No boosters while effect persists (minimum 3-month intervals). (2) Use the lowest effective dose. (3) Switch toxin types if effect diminishes (type A to type B or different brand of type A). Rappoel records each patient’s injection history, scientifically managing intervals and dosage.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Can periocular Botox be combined with other treatments? What are the contraindications?<\/div>\n<div class=\"faq-a\">Periocular Botox can be safely combined with multiple treatments: (1) Same-day \u2014 HA fillers (tear trough, nasolabial folds in different areas), PDRN injection (different facial areas), mesotherapy. As long as injections aren’t stacked at the same point. (2) 1-2 weeks apart \u2014 laser treatments (fractional laser, IPL), do laser first and wait for skin recovery before Botox, or Botox first and wait for muscle stabilization before laser. (3) 2-4 weeks apart \u2014 thread lifting, recommend thread lift first and wait for swelling to subside before Botox, to avoid swelling affecting diffusion assessment. Contraindications: (1) Active periocular infection (stye, conjunctivitis). (2) Myasthenia gravis or Lambert-Eaton syndrome. (3) Pregnancy and breastfeeding. (4) Allergy to Botox components. (5) Ptosis or incomplete eyelid closure \u2014 caution with under-eye injection. Rappoel physicians take detailed medical history before injection to rule out contraindications.<\/div>\n<\/div>\n<div class=\"cta\">\n<h3>Crow’s feet aging your smile and under-eye lines ruining makeup? Rappoel Coretox Botox \u2014 eliminate periocular wrinkles in 3 days!<\/h3>\n<p>\ud83d\udccd 77, Seocho-daero, Seocho-gu, Seoul, South Korea<\/p>\n<p>\ud83d\udd50 Mon\u2013Fri 10:00\u201319:00 \u00b7 Sat 10:00\u201317:00<\/p>\n<p>\ud83d\udcac WeChat Main: rappoelkr | WeChat Backup: rappoelkr2 | LINE: rappoelkr<\/p>\n<p style=\"margin-top:16px;font-size:13px;color:#8B7355;\">Scan to connect with us<\/p>\n<div style=\"display:flex;justify-content:center;gap:16px;flex-wrap:wrap;margin-top:10px;\">\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Rappoel\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff08\u4e3b\u53f7\uff09-1.png\" alt=\"WeChat Main QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">WeChat (Main)<\/p>\n<\/p><\/div>\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Rappoel\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff08\u5907\u7528\u53f7\uff09-1.png\" alt=\"WeChat Backup QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">WeChat (Backup)<\/p>\n<\/p><\/div>\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Line\u4e8c\u7ef4\u7801-1.jpg\" alt=\"LINE QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">LINE<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Crow’s feet aging your smile and under-eye lines ruining your makeup? Rappoel Dermatology uses Korea’s Coretox botulinum toxin \u2014 precisely relaxing the orbicularis oculi muscle for visible results in 3 days<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[66],"tags":[],"class_list":["post-1610","post","type-post","status-publish","format-standard","hentry","category-botox-en"],"_links":{"self":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1610","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/comments?post=1610"}],"version-history":[{"count":1,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1610\/revisions"}],"predecessor-version":[{"id":1612,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1610\/revisions\/1612"}],"wp:attachment":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/media?parent=1610"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/categories?post=1610"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/tags?post=1610"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

{"id":1610,"date":"2026-08-04T10:42:54","date_gmt":"2026-08-04T01:42:54","guid":{"rendered":"https:\/\/rappoel-clinic.com\/coretox-crows-feet-botox-en\/"},"modified":"2026-08-04T10:42:56","modified_gmt":"2026-08-04T01:42:56","slug":"coretox-crows-feet-botox-en","status":"publish","type":"post","link":"https:\/\/rappoel-clinic.com\/en\/coretox-crows-feet-botox-en\/","title":{"rendered":"Coretox Botox for Crow’s Feet and Eye Area Wrinkles in Seoul: Precise Treatment at Rappoel Dermatology Gangnam"},"content":{"rendered":"

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\nCoretox Botox for Crow’s Feet and Eye Area Wrinkles in Seoul: Precise Treatment at Rappoel Dermatology Gangnam<\/title><br \/>\n<meta name=\"description\" content=\"Crow's feet aging your smile and under-eye lines ruining your makeup? Rappoel Dermatology uses Korea's Coretox botulinum toxin \u2014 precisely relaxing the orbicularis oculi muscle for visible results in 3 days\">\n<link rel=\"alternate\" hreflang=\"en\" href=\"https:\/\/rappoel-clinic.com\/coretox-crows-feet-botox-en\/\" \/>\n<link rel=\"alternate\" hreflang=\"zh-TW\" href=\"https:\/\/rappoel-clinic.com\/coretox-crows-feet-botox-zh\/\" \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"MedicalClinic\", \"@id\": \"https:\/\/rappoel-clinic.com\/#clinic\", \"name\": \"Rappoel Dermatology Clinic\", \"alternateName\": [\"Rappoel \u76ae\u819a\u79d1\", \"\ub77c\ud3ec\uc5d8 \ud53c\ubd80\uacfc\"], \"url\": \"https:\/\/rappoel-clinic.com\", \"address\": {\"@type\": \"PostalAddress\", \"streetAddress\": \"77, Seocho-daero\", \"addressLocality\": \"Seocho-gu\", \"addressRegion\": \"Seoul\", \"postalCode\": \"06609\", \"addressCountry\": \"KR\"}, \"geo\": {\"@type\": \"GeoCoordinates\", \"latitude\": 37.4926, \"longitude\": 127.0175}, \"telephone\": \"+82-2-XXXX-XXXX\", \"openingHours\": [\"Mo-Fr 10:00-19:00\", \"Sa 10:00-17:00\"], \"medicalSpecialty\": \"Dermatology\", \"availableService\": [{\"@type\": \"MedicalProcedure\", \"name\": \"Thread Lift (Aptos)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Hyaluronic Acid Filler\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Botulinum Toxin (Botox)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Ultherapy \/ HIFU\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Skin Booster (Juvelook \/ Exosomes)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Laser Skin Treatment\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Onda Coolwaves Body Contouring\"}], \"sameAs\": [\"https:\/\/www.instagram.com\/rappoel_official\"]}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"Article\", \"headline\": \"Coretox Botox for Crow's Feet and Eye Area Wrinkles in Seoul: Precise Treatment at Rappoel Dermatology Gangnam\", \"description\": \"Crow's feet aging your smile and under-eye lines ruining your makeup? Rappoel Dermatology uses Korea's Coretox botulinum toxin \u2014 precisely relaxing the orbicularis oculi muscle for visible results in 3 days\", \"inLanguage\": \"en\", \"author\": {\"@type\": \"Organization\", \"name\": \"Rappoel Dermatology Clinic\"}, \"publisher\": {\"@type\": \"Organization\", \"name\": \"Rappoel Dermatology Clinic\", \"logo\": {\"@type\": \"ImageObject\", \"url\": \"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/favicon-512.png\"}}, \"about\": {\"@id\": \"https:\/\/rappoel-clinic.com\/#clinic\"}}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"Will periocular Botox affect my facial expressions? Will my smile look unnatural?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"This is the most common concern, but correct injection does not affect natural expression. The keys are: (1) Dosage control \u2014 6-12 units Coretox per side for crow's feet is the safe effective range. Rappoel's philosophy is relaxation, not complete freezing \u2014 reducing 70-80% of crow's feet contraction while preserving 20-30% natural expression. (2) Injection depth \u2014 injected in the superficial subcutaneous layer (superficial orbicularis fibers), not deep enough to reach the zygomaticus major, avoiding smile muscle interference. (3) Injection points \u2014 2-3 points per side distributed evenly in the safe zone 1-1.5cm lateral to the canthus, not near the eye corner or infraorbital margin. (4) Dynamic assessment \u2014 the physician has the patient smile repeatedly after injection to confirm natural results. Unnatural results typically occur from excessive dosage (over 15 units\/side) or too-deep injection spreading to the zygomaticus \u2014 completely avoidable by experienced physicians. Rappoel's goal is visibly reduced crow's feet when smiling while maintaining lively, natural eyes.\"}}, {\"@type\": \"Question\", \"name\": \"What is the difference between Coretox and Botox? Which is better?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Coretox and Botox are both botulinum toxin type A with the same core mechanism (blocking acetylcholine release to relax muscles), with these main differences: (1) Purity \u2014 Coretox is a 150kDa high-purity toxin with unnecessary complex proteins removed; Botox is a 900kDa complex containing auxiliary proteins. Higher purity theoretically reduces antibody formation risk \u2014 more beneficial for those needing long-term repeated injections. (2) Onset speed \u2014 Coretox averages 2-3 days onset, Botox typically 5-7 days. (3) Diffusion range \u2014 Coretox has relatively smaller diffusion, safer in delicate areas like the periocular region. (4) Preservatives \u2014 Coretox contains no animal-derived proteins or human serum albumin, lower allergy risk. (5) Origin \u2014 Coretox is domestically produced in Korea with stable supply. Rappoel selects based on patient needs \u2014 Coretox recommended for those needing fast results or experiencing diminished Botox effect; Botox also available for first-time patients or those accustomed to it. Both last similarly (4-6 months).\"}}, {\"@type\": \"Question\", \"name\": \"Can under-eye lines also be treated with Botox? Is it the same as crow's feet?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Under-eye line Botox treatment is not identical to crow's feet and requires more caution: (1) Indication selection \u2014 under-eye lines are divided into dynamic (deepened by blinking and squinting) and static (present at rest). Botox only works on dynamic under-eye lines \u2014 static lines need combination treatments (e.g., PDRN injection, laser, filler). (2) Injection location \u2014 under-eye Botox is injected 1-2mm below the lash line in the infratarsal area, 1-2 points per side, 1-2 units per point (much lower dosage than crow's feet). (3) Higher risk \u2014 under-eye injection may cause ectropion, worsened eye bags, or aggravated dry eye. Rappoel physicians assess eyelid elasticity and eye bag status before injection \u2014 those with eyelid laxity or prominent eye bags are not candidates for under-eye injection. (4) Effect \u2014 under-eye line improvement is typically less pronounced than crow's feet (due to more complex etiology). Rappoel typically recommends combined crow's feet + under-eye injection, but with very low under-eye dosage (total 2-4 units) for safety.\"}}, {\"@type\": \"Question\", \"name\": \"How long does periocular Botox last? Will I develop resistance from repeated treatments?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Periocular Botox typically lasts 4-6 months \u2014 because the neuromuscular junction gradually regenerates new acetylcholine receptors restoring muscle contraction. Factors affecting duration: (1) Individual metabolic rate \u2014 faster metabolism means faster effect fade. (2) Muscle strength \u2014 stronger orbicularis oculi may need higher dosage and lose effect faster. (3) Injection technique \u2014 precise injection into target muscle lasts longer. Regarding resistance: long-term repeated Botox injections may produce neutralizing antibodies causing diminished effect \u2014 incidence approximately 1-5%. Coretox's high-purity formulation theoretically reduces antibody risk. Strategies to minimize resistance: (1) No boosters while effect persists (minimum 3-month intervals). (2) Use the lowest effective dose. (3) Switch toxin types if effect diminishes (type A to type B or different brand of type A). Rappoel records each patient's injection history, scientifically managing intervals and dosage.\"}}, {\"@type\": \"Question\", \"name\": \"Can periocular Botox be combined with other treatments? What are the contraindications?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Periocular Botox can be safely combined with multiple treatments: (1) Same-day \u2014 HA fillers (tear trough, nasolabial folds in different areas), PDRN injection (different facial areas), mesotherapy. As long as injections aren't stacked at the same point. (2) 1-2 weeks apart \u2014 laser treatments (fractional laser, IPL), do laser first and wait for skin recovery before Botox, or Botox first and wait for muscle stabilization before laser. (3) 2-4 weeks apart \u2014 thread lifting, recommend thread lift first and wait for swelling to subside before Botox, to avoid swelling affecting diffusion assessment. Contraindications: (1) Active periocular infection (stye, conjunctivitis). (2) Myasthenia gravis or Lambert-Eaton syndrome. (3) Pregnancy and breastfeeding. (4) Allergy to Botox components. (5) Ptosis or incomplete eyelid closure \u2014 caution with under-eye injection. Rappoel physicians take detailed medical history before injection to rule out contraindications.\"}}]}<\/script><\/p>\n<style>\n*{box-sizing:border-box;margin:0;padding:0}\nbody{font-family:'PingFang SC','Noto Sans KR',sans-serif;background:#fffcf7;color:#3d2e1e;line-height:1.8}\n.wrap{max-width:677px;margin:0 auto;padding:32px 20px 60px}\n.banner{background:#FFF8EC;text-align:center;padding:36px 20px 28px;margin-bottom:36px;border-bottom:1px solid #e8d5c0}\n.banner-tag{font-size:11px;letter-spacing:3px;color:#8B7355;text-transform:uppercase;margin-bottom:12px}\n.banner h1{font-size:24px;color:#3d2e1e;line-height:1.4;margin-bottom:12px}\n.banner .sub{font-size:13px;color:#6b5240;line-height:1.7}\nh2{font-size:19px;color:#3d2e1e;margin:32px 0 14px;padding-bottom:8px;border-bottom:1px solid #e8d5c0}\nh3{font-size:16px;color:#3d2e1e;margin:22px 0 10px}\np{font-size:15px;color:#555;line-height:1.9;margin-bottom:14px}\n.highlight{background:#fff;border:1px solid #f0e8dc;border-left:3px solid #D4A574;padding:16px 20px;margin:22px 0;border-radius:0 6px 6px 0}\n.highlight p{margin:0;font-size:14px;color:#6b5240}\n.card{background:#F5E6C8;border:1px solid #e8d5c0;border-radius:8px;padding:18px 22px;margin:16px 0}\n.card-title{font-size:13px;font-weight:700;color:#3d2e1e;margin-bottom:6px}\n.card p{font-size:14px;margin:0}\n.faq-item{margin:14px 0;border-bottom:1px solid #f0e8dc;padding-bottom:14px}\n.faq-q{font-weight:700;color:#3d2e1e;font-size:15px;margin-bottom:6px}\n.faq-a{font-size:14px;color:#555;line-height:1.8}\n.cta{background:#F5E6C8;text-align:center;padding:32px 20px;margin-top:40px;border-radius:8px}\n.cta h3{font-size:17px;color:#3d2e1e;margin-bottom:8px}\n.cta p{font-size:13px;color:#6b5240;margin-bottom:4px}\nimg{max-width:100%;height:auto;display:block;margin:20px auto;border-radius:6px}\nul,ol{padding-left:22px;margin-bottom:14px}\nli{font-size:15px;color:#555;line-height:1.9;margin-bottom:4px}\n.schema-block{display:none}\n@media(max-width:600px){.wrap{padding:20px 14px 40px}.banner h1{font-size:20px}}\n<\/style>\n<p><\/head><br \/>\n<body><\/p>\n<div class=\"wrap\">\n<div class=\"banner\">\n<div class=\"banner-tag\">Botox<\/div>\n<h1>Coretox Botox for Crow’s Feet and Eye Area Wrinkles in Seoul: Precise Treatment at Rappoel Dermatology Gangnam<\/h1>\n<div class=\"sub\">Crow’s feet aging your smile and under-eye lines ruining your makeup? Rappoel Dermatology uses Korea’s Coretox botulinum toxin \u2014 precisely relaxing the orbicularis oculi muscle for visible results in 3 days<\/div>\n<\/p><\/div>\n<p>The eye area is the most fragile and age-revealing region of the face \u2014 eye skin is only 0.3-0.5mm thick (the thinnest on the face), with minimal sebaceous and sweat glands leading to poor natural hydration, combined with tens of thousands of daily blinks and rich expression muscle activity, making the eyes the first area to develop wrinkles. Periocular wrinkles are categorized into three types: (1) Crow’s feet \u2014 radiating lines extending from the outer eye corner, deepened by smiling, caused by contraction of the lateral orbicularis oculi. (2) Under-eye lines \u2014 fine horizontal lines in the under-eye area, related to orbicularis oculi contraction and skin dryness. (3) Eyelid lines \u2014 horizontal lines on the upper eyelid. Additionally, glabellar lines (between brows) and forehead lines typically appear alongside periocular wrinkles. Causes include hyperactive orbicularis oculi (dynamic wrinkles), photoaging (UVA destroying dermal collagen), skin dehydration, eye-rubbing habits, and repeated friction from eye makeup. Rappoel Dermatology near Gangnam Station, Seoul, uses Korea’s Coretox botulinum toxin \u2014 precisely injecting the lateral orbicularis oculi to safely and effectively eliminate periocular dynamic wrinkles and restore bright, youthful eyes.<\/p>\n<h2>Technical Advantages of Coretox Botulinum Toxin<\/h2>\n<ul>\n<li><strong>Korean-origin higher purity:<\/strong> Coretox is a 150kDa high-purity botulinum toxin type A developed by Daewoong Pharmaceutical \u2014 same type A as Botox (Allergan) but with different manufacturing processes. Coretox uses a unique purification process removing unnecessary complex proteins, theoretically reducing antibody formation and resistance risk \u2014 meaning for patients requiring long-term repeated injections, Coretox may maintain more consistent results over time<\/li>\n<li><strong>Faster onset (3-day results):<\/strong> Coretox clinical data shows average onset of 2-3 days, faster than traditional Botox (5-7 days) \u2014 beneficial for patients needing quick results (e.g., pre-event treatment)<\/li>\n<li><strong>Precise diffusion control:<\/strong> Coretox’s molecular properties result in smaller post-injection diffusion \u2014 particularly important in delicate areas like the periocular region, preventing toxin spread to non-target muscles (e.g., spreading to zygomaticus major causing smile asymmetry)<\/li>\n<li><strong>Preservative-free:<\/strong> Coretox formulation contains no animal-derived proteins or human serum albumin \u2014 reducing allergic reaction risk, safer for sensitive patients<\/li>\n<li><strong>Stable Korean domestic supply:<\/strong> Rappoel is located in Seoul, Korea \u2014 Coretox as a domestic product has stable supply without occasional import supply chain disruptions<\/li>\n<\/ul>\n<h2>Detailed Anatomy and Safety for Periocular Botox Injection<\/h2>\n<ul>\n<li><strong>Precise targeting of lateral orbicularis oculi:<\/strong> The treatment target for crow’s feet is the lateral orbicularis oculi (muscle fibers lateral to the outer eye corner). Injection must be 1-1.5cm lateral to the lateral canthus \u2014 too close may affect eyelid closure, too far yields insufficient effect<\/li>\n<li><strong>Avoiding zygomaticus major and risorius:<\/strong> The orbicularis oculi overlies the zygomaticus major \u2014 if toxin spreads to the zygomaticus, it causes midface drooping and smile asymmetry (crooked smile). Rappoel’s strategy: 2-3 injection points per side, 2-4 units Coretox per point, injected in the superficial subcutaneous layer (superficial orbicularis oculi), avoiding deep injection that could spread to the zygomaticus<\/li>\n<li><strong>Bony orbital rim landmark:<\/strong> All injection points are strictly lateral to the bony orbital rim \u2014 the physician palpates the orbital bone edge as a safety landmark, ensuring injections don’t enter the orbit and affect extraocular muscles<\/li>\n<li><strong>Asymmetry assessment:<\/strong> No face is perfectly symmetrical \u2014 left and right orbicularis oculi strength and wrinkle depth may differ. Rappoel physicians carefully mark bilateral wrinkle distribution before injection, adjusting dosage per side based on actual asymmetry<\/li>\n<li><strong>Avoiding over-treatment:<\/strong> Excessive orbicularis oculi injection can cause a fake smile appearance (eyes don’t move when smiling, looking unnatural) or worsened eye bags (orbicularis relaxation allows orbital fat bulging). Preserving some periocular expression is key to natural results<\/li>\n<\/ul>\n<h2>Rappoel Periocular Botox Injection Treatment Protocol<\/h2>\n<ol>\n<li><strong>Periocular assessment and plan design (10 min):<\/strong> Static and dynamic (smiling) evaluation of crow’s feet distribution and depth \u2192 assess under-eye lines \u2192 evaluate brow tail position and eyelid closure function \u2192 mark injection points (2-3 per side) \u2192 determine dosage (6-12 units Coretox per side)<\/li>\n<li><strong>Disinfection preparation (5 min):<\/strong> Facial cleansing \u2192 povidone-iodine periocular preparation \u2192 physician wears sterile gloves \u2192 30G ultra-fine insulin needle used for injection<\/li>\n<li><strong>Precise injection (5-8 min):<\/strong> 2-3 injection points per side \u2192 injection depth at superficial subcutaneous layer (superficial orbicularis oculi fibers) \u2192 2-4 units Coretox per point \u2192 gentle skin pinching during injection ensures superficial placement \u2192 immediate gentle pressure for hemostasis<\/li>\n<li><strong>Immediate assessment and guidance (5 min):<\/strong> Patient performs smiling and blinking to confirm onset of muscle relaxation \u2192 post-care instructions provided \u2192 2-week follow-up scheduled for effect evaluation<\/li>\n<\/ol>\n<p>The entire periocular Coretox injection takes only 15-20 minutes, with results visible in 3 days, full effect at 7-10 days, lasting 4-6 months. Located 3 minutes from Gangnam Station Exit 10, with seamless English and Chinese consultation.<\/p>\n<h2>Frequently Asked Questions<\/h2>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Will periocular Botox affect my facial expressions? Will my smile look unnatural?<\/div>\n<div class=\"faq-a\">This is the most common concern, but correct injection does not affect natural expression. The keys are: (1) Dosage control \u2014 6-12 units Coretox per side for crow’s feet is the safe effective range. Rappoel’s philosophy is relaxation, not complete freezing \u2014 reducing 70-80% of crow’s feet contraction while preserving 20-30% natural expression. (2) Injection depth \u2014 injected in the superficial subcutaneous layer (superficial orbicularis fibers), not deep enough to reach the zygomaticus major, avoiding smile muscle interference. (3) Injection points \u2014 2-3 points per side distributed evenly in the safe zone 1-1.5cm lateral to the canthus, not near the eye corner or infraorbital margin. (4) Dynamic assessment \u2014 the physician has the patient smile repeatedly after injection to confirm natural results. Unnatural results typically occur from excessive dosage (over 15 units\/side) or too-deep injection spreading to the zygomaticus \u2014 completely avoidable by experienced physicians. Rappoel’s goal is visibly reduced crow’s feet when smiling while maintaining lively, natural eyes.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">What is the difference between Coretox and Botox? Which is better?<\/div>\n<div class=\"faq-a\">Coretox and Botox are both botulinum toxin type A with the same core mechanism (blocking acetylcholine release to relax muscles), with these main differences: (1) Purity \u2014 Coretox is a 150kDa high-purity toxin with unnecessary complex proteins removed; Botox is a 900kDa complex containing auxiliary proteins. Higher purity theoretically reduces antibody formation risk \u2014 more beneficial for those needing long-term repeated injections. (2) Onset speed \u2014 Coretox averages 2-3 days onset, Botox typically 5-7 days. (3) Diffusion range \u2014 Coretox has relatively smaller diffusion, safer in delicate areas like the periocular region. (4) Preservatives \u2014 Coretox contains no animal-derived proteins or human serum albumin, lower allergy risk. (5) Origin \u2014 Coretox is domestically produced in Korea with stable supply. Rappoel selects based on patient needs \u2014 Coretox recommended for those needing fast results or experiencing diminished Botox effect; Botox also available for first-time patients or those accustomed to it. Both last similarly (4-6 months).<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Can under-eye lines also be treated with Botox? Is it the same as crow’s feet?<\/div>\n<div class=\"faq-a\">Under-eye line Botox treatment is not identical to crow’s feet and requires more caution: (1) Indication selection \u2014 under-eye lines are divided into dynamic (deepened by blinking and squinting) and static (present at rest). Botox only works on dynamic under-eye lines \u2014 static lines need combination treatments (e.g., PDRN injection, laser, filler). (2) Injection location \u2014 under-eye Botox is injected 1-2mm below the lash line in the infratarsal area, 1-2 points per side, 1-2 units per point (much lower dosage than crow’s feet). (3) Higher risk \u2014 under-eye injection may cause ectropion, worsened eye bags, or aggravated dry eye. Rappoel physicians assess eyelid elasticity and eye bag status before injection \u2014 those with eyelid laxity or prominent eye bags are not candidates for under-eye injection. (4) Effect \u2014 under-eye line improvement is typically less pronounced than crow’s feet (due to more complex etiology). Rappoel typically recommends combined crow’s feet + under-eye injection, but with very low under-eye dosage (total 2-4 units) for safety.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">How long does periocular Botox last? Will I develop resistance from repeated treatments?<\/div>\n<div class=\"faq-a\">Periocular Botox typically lasts 4-6 months \u2014 because the neuromuscular junction gradually regenerates new acetylcholine receptors restoring muscle contraction. Factors affecting duration: (1) Individual metabolic rate \u2014 faster metabolism means faster effect fade. (2) Muscle strength \u2014 stronger orbicularis oculi may need higher dosage and lose effect faster. (3) Injection technique \u2014 precise injection into target muscle lasts longer. Regarding resistance: long-term repeated Botox injections may produce neutralizing antibodies causing diminished effect \u2014 incidence approximately 1-5%. Coretox’s high-purity formulation theoretically reduces antibody risk. Strategies to minimize resistance: (1) No boosters while effect persists (minimum 3-month intervals). (2) Use the lowest effective dose. (3) Switch toxin types if effect diminishes (type A to type B or different brand of type A). Rappoel records each patient’s injection history, scientifically managing intervals and dosage.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Can periocular Botox be combined with other treatments? What are the contraindications?<\/div>\n<div class=\"faq-a\">Periocular Botox can be safely combined with multiple treatments: (1) Same-day \u2014 HA fillers (tear trough, nasolabial folds in different areas), PDRN injection (different facial areas), mesotherapy. As long as injections aren’t stacked at the same point. (2) 1-2 weeks apart \u2014 laser treatments (fractional laser, IPL), do laser first and wait for skin recovery before Botox, or Botox first and wait for muscle stabilization before laser. (3) 2-4 weeks apart \u2014 thread lifting, recommend thread lift first and wait for swelling to subside before Botox, to avoid swelling affecting diffusion assessment. Contraindications: (1) Active periocular infection (stye, conjunctivitis). (2) Myasthenia gravis or Lambert-Eaton syndrome. (3) Pregnancy and breastfeeding. (4) Allergy to Botox components. (5) Ptosis or incomplete eyelid closure \u2014 caution with under-eye injection. Rappoel physicians take detailed medical history before injection to rule out contraindications.<\/div>\n<\/div>\n<div class=\"cta\">\n<h3>Crow’s feet aging your smile and under-eye lines ruining makeup? Rappoel Coretox Botox \u2014 eliminate periocular wrinkles in 3 days!<\/h3>\n<p>\ud83d\udccd 77, Seocho-daero, Seocho-gu, Seoul, South Korea<\/p>\n<p>\ud83d\udd50 Mon\u2013Fri 10:00\u201319:00 \u00b7 Sat 10:00\u201317:00<\/p>\n<p>\ud83d\udcac WeChat Main: rappoelkr | WeChat Backup: rappoelkr2 | LINE: rappoelkr<\/p>\n<p style=\"margin-top:16px;font-size:13px;color:#8B7355;\">Scan to connect with us<\/p>\n<div style=\"display:flex;justify-content:center;gap:16px;flex-wrap:wrap;margin-top:10px;\">\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Rappoel\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff08\u4e3b\u53f7\uff09-1.png\" alt=\"WeChat Main QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">WeChat (Main)<\/p>\n<\/p><\/div>\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Rappoel\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff08\u5907\u7528\u53f7\uff09-1.png\" alt=\"WeChat Backup QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">WeChat (Backup)<\/p>\n<\/p><\/div>\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Line\u4e8c\u7ef4\u7801-1.jpg\" alt=\"LINE QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">LINE<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Crow’s feet aging your smile and under-eye lines ruining your makeup? Rappoel Dermatology uses Korea’s Coretox botulinum toxin \u2014 precisely relaxing the orbicularis oculi muscle for visible results in 3 days<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[66],"tags":[],"class_list":["post-1610","post","type-post","status-publish","format-standard","hentry","category-botox-en"],"_links":{"self":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1610","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/comments?post=1610"}],"version-history":[{"count":1,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1610\/revisions"}],"predecessor-version":[{"id":1612,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1610\/revisions\/1612"}],"wp:attachment":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/media?parent=1610"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/categories?post=1610"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/tags?post=1610"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}