Botox Hyperhidrosis Treatment in Seoul: Coretox Injection for Excessive Sweating at Rappoel Dermatology Gangnam<\/title><br \/>\n<meta name=\"description\" content=\"Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts, foot sweat keeping shoes damp? Rappoel Dermatology uses Coretox botulinum toxin injection \u2014 precisely blocking sweat gland nerve signals, results in 5-7 days lasting 6-9 months\">\n<link rel=\"alternate\" hreflang=\"en\" href=\"https:\/\/rappoel-clinic.com\/coretox-botox-hyperhidrosis-treatment-en\/\" \/>\n<link rel=\"alternate\" hreflang=\"zh-TW\" href=\"https:\/\/rappoel-clinic.com\/coretox-botox-hyperhidrosis-treatment-zh\/\" \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"MedicalClinic\", \"@id\": \"https:\/\/rappoel-clinic.com\/#clinic\", \"name\": \"Rappoel Dermatology Clinic\", \"alternateName\": [\"Rappoel \u76ae\u819a\u79d1\", \"\ub77c\ud3ec\uc5d8 \ud53c\ubd80\uacfc\"], \"url\": \"https:\/\/rappoel-clinic.com\", \"address\": {\"@type\": \"PostalAddress\", \"streetAddress\": \"77, Seocho-daero\", \"addressLocality\": \"Seocho-gu\", \"addressRegion\": \"Seoul\", \"postalCode\": \"06609\", \"addressCountry\": \"KR\"}, \"geo\": {\"@type\": \"GeoCoordinates\", \"latitude\": 37.4926, \"longitude\": 127.0175}, \"telephone\": \"+82-2-XXXX-XXXX\", \"openingHours\": [\"Mo-Fr 10:00-19:00\", \"Sa 10:00-17:00\"], \"medicalSpecialty\": \"Dermatology\", \"availableService\": [{\"@type\": \"MedicalProcedure\", \"name\": \"Thread Lift (Aptos)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Hyaluronic Acid Filler\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Botulinum Toxin (Botox)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Ultherapy \/ HIFU\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Skin Booster (Juvelook \/ Exosomes)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Laser Skin Treatment\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Onda Coolwaves Body Contouring\"}], \"sameAs\": [\"https:\/\/www.instagram.com\/rappoel_official\"]}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"Article\", \"headline\": \"Botox Hyperhidrosis Treatment in Seoul: Coretox Injection for Excessive Sweating at Rappoel Dermatology Gangnam\", \"description\": \"Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts, foot sweat keeping shoes damp? Rappoel Dermatology uses Coretox botulinum toxin injection \u2014 precisely blocking sweat gland nerve signals, results in 5-7 days lasting 6-9 months\", \"inLanguage\": \"en\", \"author\": {\"@type\": \"Organization\", \"name\": \"Rappoel Dermatology Clinic\"}, \"publisher\": {\"@type\": \"Organization\", \"name\": \"Rappoel Dermatology Clinic\", \"logo\": {\"@type\": \"ImageObject\", \"url\": \"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/favicon-512.png\"}}, \"about\": {\"@id\": \"https:\/\/rappoel-clinic.com\/#clinic\"}}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"What's the difference between Botox antiperspirant and antiperspirant deodorants\/roll-ons?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Completely different action levels: (1) Antiperspirants (aluminum-based) \u2014 form gel-like plugs at sweat duct openings physically blocking sweat discharge. Limited efficacy (20-30% sweat reduction), effective only for mild cases, requires daily use, long-term use may irritate skin and yellow clothing. Prescription-grade 20%+ aluminum chloride is somewhat more effective but may cause irritation and itching. (2) Botulinum toxin injection \u2014 blocks sweat gland secretion signals at the neural level, with 70-90% antiperspirant efficacy, one injection lasting 6-9 months. Suitable for moderate-to-severe hyperhidrosis unresponsive to or intolerant of antiperspirants. Rappoel recommends: mild hyperhidrosis may try prescription-grade aluminum chloride first, then consider botulinum toxin if ineffective or unsatisfactory. Botulinum toxin isn't a last resort \u2014 for hyperhidrosis severely impacting social life, choosing it directly can rapidly improve quality of life without prolonged ineffective antiperspirant trial periods.\"}}, {\"@type\": \"Question\", \"name\": \"Will Botox injection for palmar hyperhidrosis cause hand numbness or muscle weakness?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"With proper technique, no muscle weakness occurs \u2014 but palm injection is indeed the most technically demanding site. Key lies in injection depth: palmar sweat glands are in the mid-dermis (approximately 2-3mm deep), while hand muscles (lumbricals, interossei) are in the deeper subfascial layer. Injection in the mid-dermis acts only on sweat glands without affecting muscles. However, palmar skin is extremely thick and dense with high injection resistance \u2014 requiring experienced physician depth control. Possible mild side effects: (1) Transient hand muscle weakness \u2014 extremely rare, caused by overly deep injection with diffusion to muscle layer, self-resolves in 2-4 weeks. (2) Finger numbness \u2014 extremely rare, from needle contacting digital nerve branches. (3) Significant injection pain \u2014 palms are among the most nerve-dense and painful injection sites; Rappoel uses ice + vibration anesthesia + 32G ultra-fine needles to reduce pain to tolerable levels. Choosing an experienced physician is key to safety.\"}}, {\"@type\": \"Question\", \"name\": \"Will compensatory sweating increase elsewhere after axillary Botox injection?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"No \u2014 this is botulinum toxin's greatest advantage over sympathectomy surgery. Endoscopic thoracic sympathectomy (ETS) cuts the sympathetic chain governing palms to stop palmar sweating \u2014 approximately 30-50% of patients develop compensatory hyperhidrosis (significantly increased sweating in other areas like the back, abdomen, thighs to compensate). Botulinum toxin only blocks sweat glands in the injected area \u2014 without altering overall sympathetic signaling \u2014 sweat glands elsewhere are completely unaffected. Injecting axillae only stops axillary sweating, injecting palms only stops palmar sweating \u2014 precise selective antiperspirant with zero compensatory risk. This is also why botulinum toxin can be repeatedly injected and used at multiple sites simultaneously safely \u2014 palms + axillae + soles can be injected the same day without interference.\"}}, {\"@type\": \"Question\", \"name\": \"How long do Botox antiperspirant results last? How often do I need injections?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Duration varies by site and individual: Axillae \u2014 antiperspirant effect typically lasts 7-9 months (axillary sweat glands are most sensitive to botulinum toxin with slower metabolism); Palms \u2014 6-8 months; Soles \u2014 6-7 months (thick plantar stratum corneum affects drug diffusion). The first year typically requires 2 injections (6-7 month intervals), potentially extending to once yearly in the second year (some patients report cumulative duration extension with repeated injections \u2014 possibly from partial sweat gland atrophy after prolonged inhibition). Rappoel recommends: 2-week post-injection follow-up to assess \u2014 if satisfactory (70%+ sweat reduction), schedule the second injection at 6 months; if suboptimal (under 50% reduction), dose increase or protocol adjustment may be needed. Twice-yearly injections maintain year-round dryness.\"}}, {\"@type\": \"Question\", \"name\": \"Are there contraindications for Botox hyperhidrosis treatment? Who is not suitable?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Contraindicated groups include: (1) Pregnant and breastfeeding women \u2014 while injection doses are small and locally acting, pregnancy injection is not recommended for safety. (2) Those allergic to botulinum toxin or excipients \u2014 extremely rare but requires confirmation. (3) Active infection at injection sites \u2014 such as axillary folliculitis or skin infection; must be treated before injection. (4) Neuromuscular disease patients \u2014 such as myasthenia gravis, Eaton-Lambert syndrome \u2014 botulinum toxin may exacerbate symptoms. (5) Coagulation disorders \u2014 discontinue anticoagulants (e.g., aspirin) 1 week before injection. Suitable candidates: (1) Moderate-to-severe primary focal hyperhidrosis (sweating significantly impacting social and work life). (2) Those unresponsive to or intolerant of antiperspirants. (3) Those unwilling to undergo sympathectomy or with post-surgical compensatory hyperhidrosis. Rappoel conducts detailed consultation and assessment before injection to ensure safe applicability.\"}}]}<\/script><\/p>\n<style>\n*{box-sizing:border-box;margin:0;padding:0}\nbody{font-family:'PingFang SC','Noto Sans KR',sans-serif;background:#fffcf7;color:#3d2e1e;line-height:1.8}\n.wrap{max-width:677px;margin:0 auto;padding:32px 20px 60px}\n.banner{background:#FFF8EC;text-align:center;padding:36px 20px 28px;margin-bottom:36px;border-bottom:1px solid #e8d5c0}\n.banner-tag{font-size:11px;letter-spacing:3px;color:#8B7355;text-transform:uppercase;margin-bottom:12px}\n.banner h1{font-size:24px;color:#3d2e1e;line-height:1.4;margin-bottom:12px}\n.banner .sub{font-size:13px;color:#6b5240;line-height:1.7}\nh2{font-size:19px;color:#3d2e1e;margin:32px 0 14px;padding-bottom:8px;border-bottom:1px solid #e8d5c0}\nh3{font-size:16px;color:#3d2e1e;margin:22px 0 10px}\np{font-size:15px;color:#555;line-height:1.9;margin-bottom:14px}\n.highlight{background:#fff;border:1px solid #f0e8dc;border-left:3px solid #D4A574;padding:16px 20px;margin:22px 0;border-radius:0 6px 6px 0}\n.highlight p{margin:0;font-size:14px;color:#6b5240}\n.card{background:#F5E6C8;border:1px solid #e8d5c0;border-radius:8px;padding:18px 22px;margin:16px 0}\n.card-title{font-size:13px;font-weight:700;color:#3d2e1e;margin-bottom:6px}\n.card p{font-size:14px;margin:0}\n.faq-item{margin:14px 0;border-bottom:1px solid #f0e8dc;padding-bottom:14px}\n.faq-q{font-weight:700;color:#3d2e1e;font-size:15px;margin-bottom:6px}\n.faq-a{font-size:14px;color:#555;line-height:1.8}\n.cta{background:#F5E6C8;text-align:center;padding:32px 20px;margin-top:40px;border-radius:8px}\n.cta h3{font-size:17px;color:#3d2e1e;margin-bottom:8px}\n.cta p{font-size:13px;color:#6b5240;margin-bottom:4px}\nimg{max-width:100%;height:auto;display:block;margin:20px auto;border-radius:6px}\nul,ol{padding-left:22px;margin-bottom:14px}\nli{font-size:15px;color:#555;line-height:1.9;margin-bottom:4px}\n.schema-block{display:none}\n@media(max-width:600px){.wrap{padding:20px 14px 40px}.banner h1{font-size:20px}}\n<\/style>\n<p><\/head><br \/>\n<body><\/p>\n<div class=\"wrap\">\n<div class=\"banner\">\n<div class=\"banner-tag\">Botox<\/div>\n<h1>Botox Hyperhidrosis Treatment in Seoul: Coretox Injection for Excessive Sweating at Rappoel Dermatology Gangnam<\/h1>\n<div class=\"sub\">Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts, foot sweat keeping shoes damp? Rappoel Dermatology uses Coretox botulinum toxin injection \u2014 precisely blocking sweat gland nerve signals, results in 5-7 days lasting 6-9 months<\/div>\n<\/p><\/div>\n<p>Hyperhidrosis is a severely underestimated invisible affliction \u2014 not painful, itchy, or life-threatening, but its negative impact on social, professional, and psychological well-being may exceed many visible conditions. Primary focal hyperhidrosis affects approximately 3% of the global population, typically onset at puberty and persisting lifelong. The distressing scenarios are everywhere: the other person feeling your cold damp palm during a handshake, underarm sweat stains spreading in circles on your shirt during important meetings, constant worry when wearing light-colored clothing, foot sweat odor embarrassment when removing shoes, sweat drops on keyboard screens, fingers slipping on phones… These accumulated scenarios severely undermine self-confidence. The root cause of hyperhidrosis lies in overactive sweat glands \u2014 not from deficiency or weakness, but from hyperactive sympathetic nerve signals governing sweat glands. Rappoel Dermatology near Gangnam Station, Seoul, uses Coretox botulinum toxin injection \u2014 temporarily switching off overactive sweat glands by blocking acetylcholine release, providing a safe and highly effective antiperspirant solution.<\/p>\n<h2>Scientific Mechanism of Hyperhidrosis \u2014 Not Weakness, But Neural Hyperactivity<\/h2>\n<ul>\n<li><strong>Sweat gland innervation:<\/strong> The human body has approximately 2-4 million sweat glands, concentrated in palms, soles, axillae, and forehead. Sweat glands are sympathetically innervated \u2014 sympathetic nerve terminals release acetylcholine (ACh), which binds muscarinic receptors on sweat glands triggering sweat secretion. Normally this system activates for thermoregulation during exercise or heat; hyperhidrosis patients’ sympathetic nerves continuously release excess ACh at normal temperatures<\/li>\n<li><strong>Primary focal hyperhidrosis:<\/strong> The most common type \u2014 presenting as symmetric excessive sweating of palms, axillae, and soles without systemic disease. Pathogenesis involves sympathetic ganglion hyperexcitability with possible genetic predisposition (approximately 30-50% have family history)<\/li>\n<li><strong>Secondary generalized hyperhidrosis:<\/strong> Caused by hyperthyroidism, diabetes, menopause, certain medications, or infections \u2014 requiring treatment of the underlying condition; botulinum toxin is not applicable<\/li>\n<li><strong>Emotional hyperhidrosis:<\/strong> Excessive sweating triggered by stress, anxiety, or social pressure \u2014 related to sympathetic nerve overreaction to emotional stimuli. The vicious cycle: sweating \u2192 anxiety \u2192 more sweating<\/li>\n<li><strong>Starch-iodine test grading:<\/strong> Rappoel uses the Minor’s starch-iodine test to precisely assess sweating area and severity \u2014 iodine solution applied, starch powder sprinkled, sweating areas turn blue-purple, with area and color depth reflecting sweat volume<\/li>\n<\/ul>\n<h2>Coretox Botulinum Toxin Antiperspirant Mechanism<\/h2>\n<ul>\n<li><strong>ACh release blockade:<\/strong> Coretox (Botulinum Toxin Type A) injected into sweat gland-dense areas \u2014 taken up by sympathetic nerve terminals and cleaves SNAP-25 protein (essential for vesicle fusion) \u2014 preventing acetylcholine vesicles from fusing with the cell membrane for release \u2014 sweat glands receive no secretion signal and stop producing sweat<\/li>\n<li><strong>Selective antiperspirant:<\/strong> Botulinum toxin only blocks sweat glands in the injected area \u2014 systemic thermoregulation is unaffected (sweat glands outside the injection zone work normally) \u2014 no hyperthermia or compensatory hyperhidrosis elsewhere<\/li>\n<li><strong>Coretox advantages:<\/strong> Manufactured by Korea’s Hugel \u2014 free of animal proteins and lactose (reducing allergy risk), low diffusion (minimal spread from injection point, minimizing impact on surrounding muscles \u2014 particularly important for palm injections to avoid hand muscle weakness)<\/li>\n<li><strong>5-7 day onset:<\/strong> ACh release is blocked immediately after injection, but already-released ACh requires days for metabolism \u2014 typically 5-7 days for significant sweat reduction (70-90% decrease), with peak antiperspirant effect at 2 weeks<\/li>\n<li><strong>6-9 month duration:<\/strong> Nerve terminals gradually sprout new synapses over 3-6 months restoring ACh release \u2014 antiperspirant effect gradually diminishes. Typically one injection lasts 6-9 months (significant individual variation), with repeated injections potentially extending duration<\/li>\n<\/ul>\n<h2>Rappoel Hyperhidrosis Botox Injection Treatment Protocol<\/h2>\n<ol>\n<li><strong>Sweating assessment and starch-iodine test (15 min):<\/strong> Iodine solution evenly applied to target area (palms\/axillae\/soles) \u2192 starch powder sprinkled \u2192 5-minute wait \u2192 photography documenting sweating area and severity \u2192 marking severe sweating zones as priority injection areas<\/li>\n<li><strong>Disinfection and anesthesia (20 min):<\/strong> Povidone-iodine preparation of target area \u2192 ice packs or vibration anesthesia for palms and soles (more painful injection sites) \u2192 axillae typically require no additional anesthesia (tolerable pain)<\/li>\n<li><strong>Multi-point botulinum toxin injection (15-30 min):<\/strong> 30G\/32G ultra-fine needle for uniform grid injection \u2014 axillae 10-15 points per side, 2 units per point (50-100 units per side total); palms 20-30 points per side, 1-2 units per point (50-100 units per side total); soles 20-30 points per side, 1-2 units per point (50-100 units per side total)<\/li>\n<li><strong>Post-treatment observation and care instructions (10 min):<\/strong> Apply pressure for hemostasis 5 minutes \u2192 instruct no water contact or strenuous exercise for 24 hours \u2192 schedule 2-week follow-up to assess antiperspirant effect<\/li>\n<\/ol>\n<p>Botulinum toxin hyperhidrosis treatment is a life-changing social lifeline \u2014 many patients say after their first treatment, I can finally shake hands confidently or I can finally wear light-colored clothing. Results in 5-7 days, 6-9 months of dryness, with twice-yearly injections for year-round relief. Located 3 minutes from Gangnam Station Exit 10, with seamless English and Chinese consultation.<\/p>\n<h2>Frequently Asked Questions<\/h2>\n<div class=\"faq-item\">\n<div class=\"faq-q\">What’s the difference between Botox antiperspirant and antiperspirant deodorants\/roll-ons?<\/div>\n<div class=\"faq-a\">Completely different action levels: (1) Antiperspirants (aluminum-based) \u2014 form gel-like plugs at sweat duct openings physically blocking sweat discharge. Limited efficacy (20-30% sweat reduction), effective only for mild cases, requires daily use, long-term use may irritate skin and yellow clothing. Prescription-grade 20%+ aluminum chloride is somewhat more effective but may cause irritation and itching. (2) Botulinum toxin injection \u2014 blocks sweat gland secretion signals at the neural level, with 70-90% antiperspirant efficacy, one injection lasting 6-9 months. Suitable for moderate-to-severe hyperhidrosis unresponsive to or intolerant of antiperspirants. Rappoel recommends: mild hyperhidrosis may try prescription-grade aluminum chloride first, then consider botulinum toxin if ineffective or unsatisfactory. Botulinum toxin isn’t a last resort \u2014 for hyperhidrosis severely impacting social life, choosing it directly can rapidly improve quality of life without prolonged ineffective antiperspirant trial periods.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Will Botox injection for palmar hyperhidrosis cause hand numbness or muscle weakness?<\/div>\n<div class=\"faq-a\">With proper technique, no muscle weakness occurs \u2014 but palm injection is indeed the most technically demanding site. Key lies in injection depth: palmar sweat glands are in the mid-dermis (approximately 2-3mm deep), while hand muscles (lumbricals, interossei) are in the deeper subfascial layer. Injection in the mid-dermis acts only on sweat glands without affecting muscles. However, palmar skin is extremely thick and dense with high injection resistance \u2014 requiring experienced physician depth control. Possible mild side effects: (1) Transient hand muscle weakness \u2014 extremely rare, caused by overly deep injection with diffusion to muscle layer, self-resolves in 2-4 weeks. (2) Finger numbness \u2014 extremely rare, from needle contacting digital nerve branches. (3) Significant injection pain \u2014 palms are among the most nerve-dense and painful injection sites; Rappoel uses ice + vibration anesthesia + 32G ultra-fine needles to reduce pain to tolerable levels. Choosing an experienced physician is key to safety.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Will compensatory sweating increase elsewhere after axillary Botox injection?<\/div>\n<div class=\"faq-a\">No \u2014 this is botulinum toxin’s greatest advantage over sympathectomy surgery. Endoscopic thoracic sympathectomy (ETS) cuts the sympathetic chain governing palms to stop palmar sweating \u2014 approximately 30-50% of patients develop compensatory hyperhidrosis (significantly increased sweating in other areas like the back, abdomen, thighs to compensate). Botulinum toxin only blocks sweat glands in the injected area \u2014 without altering overall sympathetic signaling \u2014 sweat glands elsewhere are completely unaffected. Injecting axillae only stops axillary sweating, injecting palms only stops palmar sweating \u2014 precise selective antiperspirant with zero compensatory risk. This is also why botulinum toxin can be repeatedly injected and used at multiple sites simultaneously safely \u2014 palms + axillae + soles can be injected the same day without interference.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">How long do Botox antiperspirant results last? How often do I need injections?<\/div>\n<div class=\"faq-a\">Duration varies by site and individual: Axillae \u2014 antiperspirant effect typically lasts 7-9 months (axillary sweat glands are most sensitive to botulinum toxin with slower metabolism); Palms \u2014 6-8 months; Soles \u2014 6-7 months (thick plantar stratum corneum affects drug diffusion). The first year typically requires 2 injections (6-7 month intervals), potentially extending to once yearly in the second year (some patients report cumulative duration extension with repeated injections \u2014 possibly from partial sweat gland atrophy after prolonged inhibition). Rappoel recommends: 2-week post-injection follow-up to assess \u2014 if satisfactory (70%+ sweat reduction), schedule the second injection at 6 months; if suboptimal (under 50% reduction), dose increase or protocol adjustment may be needed. Twice-yearly injections maintain year-round dryness.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Are there contraindications for Botox hyperhidrosis treatment? Who is not suitable?<\/div>\n<div class=\"faq-a\">Contraindicated groups include: (1) Pregnant and breastfeeding women \u2014 while injection doses are small and locally acting, pregnancy injection is not recommended for safety. (2) Those allergic to botulinum toxin or excipients \u2014 extremely rare but requires confirmation. (3) Active infection at injection sites \u2014 such as axillary folliculitis or skin infection; must be treated before injection. (4) Neuromuscular disease patients \u2014 such as myasthenia gravis, Eaton-Lambert syndrome \u2014 botulinum toxin may exacerbate symptoms. (5) Coagulation disorders \u2014 discontinue anticoagulants (e.g., aspirin) 1 week before injection. Suitable candidates: (1) Moderate-to-severe primary focal hyperhidrosis (sweating significantly impacting social and work life). (2) Those unresponsive to or intolerant of antiperspirants. (3) Those unwilling to undergo sympathectomy or with post-surgical compensatory hyperhidrosis. Rappoel conducts detailed consultation and assessment before injection to ensure safe applicability.<\/div>\n<\/div>\n<div class=\"cta\">\n<h3>Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts? Coretox botulinum toxin hyperhidrosis treatment \u2014 results in 5-7 days, 6-9 months of confident dryness!<\/h3>\n<p>\ud83d\udccd 77, Seocho-daero, Seocho-gu, Seoul, South Korea<\/p>\n<p>\ud83d\udd50 Mon\u2013Fri 10:00\u201319:00 \u00b7 Sat 10:00\u201317:00<\/p>\n<p>\ud83d\udcac WeChat Main: rappoelkr | WeChat Backup: rappoelkr2 | LINE: rappoelkr<\/p>\n<p style=\"margin-top:16px;font-size:13px;color:#8B7355;\">Scan to connect with us<\/p>\n<div style=\"display:flex;justify-content:center;gap:16px;flex-wrap:wrap;margin-top:10px;\">\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Rappoel\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff08\u4e3b\u53f7\uff09-1.png\" alt=\"WeChat Main QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">WeChat (Main)<\/p>\n<\/p><\/div>\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Rappoel\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff08\u5907\u7528\u53f7\uff09-1.png\" alt=\"WeChat Backup QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">WeChat (Backup)<\/p>\n<\/p><\/div>\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Line\u4e8c\u7ef4\u7801-1.jpg\" alt=\"LINE QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">LINE<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts, foot sweat keeping shoes damp? Rappoel Dermatology uses Coretox botulinum toxin injection \u2014 precisely blocking sweat gland nerve signals, results in 5-7 days lasting 6-9 months<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[66],"tags":[],"class_list":["post-1598","post","type-post","status-publish","format-standard","hentry","category-botox-en"],"_links":{"self":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1598","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/comments?post=1598"}],"version-history":[{"count":1,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1598\/revisions"}],"predecessor-version":[{"id":1600,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1598\/revisions\/1600"}],"wp:attachment":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/media?parent=1598"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/categories?post=1598"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/tags?post=1598"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

{"id":1598,"date":"2026-08-03T16:40:29","date_gmt":"2026-08-03T07:40:29","guid":{"rendered":"https:\/\/rappoel-clinic.com\/coretox-botox-hyperhidrosis-treatment-en\/"},"modified":"2026-08-03T16:40:32","modified_gmt":"2026-08-03T07:40:32","slug":"coretox-botox-hyperhidrosis-treatment-en","status":"publish","type":"post","link":"https:\/\/rappoel-clinic.com\/en\/coretox-botox-hyperhidrosis-treatment-en\/","title":{"rendered":"Botox Hyperhidrosis Treatment in Seoul: Coretox Injection for Excessive Sweating at Rappoel Dermatology Gangnam"},"content":{"rendered":"

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\nBotox Hyperhidrosis Treatment in Seoul: Coretox Injection for Excessive Sweating at Rappoel Dermatology Gangnam<\/title><br \/>\n<meta name=\"description\" content=\"Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts, foot sweat keeping shoes damp? Rappoel Dermatology uses Coretox botulinum toxin injection \u2014 precisely blocking sweat gland nerve signals, results in 5-7 days lasting 6-9 months\">\n<link rel=\"alternate\" hreflang=\"en\" href=\"https:\/\/rappoel-clinic.com\/coretox-botox-hyperhidrosis-treatment-en\/\" \/>\n<link rel=\"alternate\" hreflang=\"zh-TW\" href=\"https:\/\/rappoel-clinic.com\/coretox-botox-hyperhidrosis-treatment-zh\/\" \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"MedicalClinic\", \"@id\": \"https:\/\/rappoel-clinic.com\/#clinic\", \"name\": \"Rappoel Dermatology Clinic\", \"alternateName\": [\"Rappoel \u76ae\u819a\u79d1\", \"\ub77c\ud3ec\uc5d8 \ud53c\ubd80\uacfc\"], \"url\": \"https:\/\/rappoel-clinic.com\", \"address\": {\"@type\": \"PostalAddress\", \"streetAddress\": \"77, Seocho-daero\", \"addressLocality\": \"Seocho-gu\", \"addressRegion\": \"Seoul\", \"postalCode\": \"06609\", \"addressCountry\": \"KR\"}, \"geo\": {\"@type\": \"GeoCoordinates\", \"latitude\": 37.4926, \"longitude\": 127.0175}, \"telephone\": \"+82-2-XXXX-XXXX\", \"openingHours\": [\"Mo-Fr 10:00-19:00\", \"Sa 10:00-17:00\"], \"medicalSpecialty\": \"Dermatology\", \"availableService\": [{\"@type\": \"MedicalProcedure\", \"name\": \"Thread Lift (Aptos)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Hyaluronic Acid Filler\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Botulinum Toxin (Botox)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Ultherapy \/ HIFU\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Skin Booster (Juvelook \/ Exosomes)\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Laser Skin Treatment\"}, {\"@type\": \"MedicalProcedure\", \"name\": \"Onda Coolwaves Body Contouring\"}], \"sameAs\": [\"https:\/\/www.instagram.com\/rappoel_official\"]}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"Article\", \"headline\": \"Botox Hyperhidrosis Treatment in Seoul: Coretox Injection for Excessive Sweating at Rappoel Dermatology Gangnam\", \"description\": \"Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts, foot sweat keeping shoes damp? Rappoel Dermatology uses Coretox botulinum toxin injection \u2014 precisely blocking sweat gland nerve signals, results in 5-7 days lasting 6-9 months\", \"inLanguage\": \"en\", \"author\": {\"@type\": \"Organization\", \"name\": \"Rappoel Dermatology Clinic\"}, \"publisher\": {\"@type\": \"Organization\", \"name\": \"Rappoel Dermatology Clinic\", \"logo\": {\"@type\": \"ImageObject\", \"url\": \"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/favicon-512.png\"}}, \"about\": {\"@id\": \"https:\/\/rappoel-clinic.com\/#clinic\"}}<\/script><br \/>\n<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"What's the difference between Botox antiperspirant and antiperspirant deodorants\/roll-ons?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Completely different action levels: (1) Antiperspirants (aluminum-based) \u2014 form gel-like plugs at sweat duct openings physically blocking sweat discharge. Limited efficacy (20-30% sweat reduction), effective only for mild cases, requires daily use, long-term use may irritate skin and yellow clothing. Prescription-grade 20%+ aluminum chloride is somewhat more effective but may cause irritation and itching. (2) Botulinum toxin injection \u2014 blocks sweat gland secretion signals at the neural level, with 70-90% antiperspirant efficacy, one injection lasting 6-9 months. Suitable for moderate-to-severe hyperhidrosis unresponsive to or intolerant of antiperspirants. Rappoel recommends: mild hyperhidrosis may try prescription-grade aluminum chloride first, then consider botulinum toxin if ineffective or unsatisfactory. Botulinum toxin isn't a last resort \u2014 for hyperhidrosis severely impacting social life, choosing it directly can rapidly improve quality of life without prolonged ineffective antiperspirant trial periods.\"}}, {\"@type\": \"Question\", \"name\": \"Will Botox injection for palmar hyperhidrosis cause hand numbness or muscle weakness?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"With proper technique, no muscle weakness occurs \u2014 but palm injection is indeed the most technically demanding site. Key lies in injection depth: palmar sweat glands are in the mid-dermis (approximately 2-3mm deep), while hand muscles (lumbricals, interossei) are in the deeper subfascial layer. Injection in the mid-dermis acts only on sweat glands without affecting muscles. However, palmar skin is extremely thick and dense with high injection resistance \u2014 requiring experienced physician depth control. Possible mild side effects: (1) Transient hand muscle weakness \u2014 extremely rare, caused by overly deep injection with diffusion to muscle layer, self-resolves in 2-4 weeks. (2) Finger numbness \u2014 extremely rare, from needle contacting digital nerve branches. (3) Significant injection pain \u2014 palms are among the most nerve-dense and painful injection sites; Rappoel uses ice + vibration anesthesia + 32G ultra-fine needles to reduce pain to tolerable levels. Choosing an experienced physician is key to safety.\"}}, {\"@type\": \"Question\", \"name\": \"Will compensatory sweating increase elsewhere after axillary Botox injection?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"No \u2014 this is botulinum toxin's greatest advantage over sympathectomy surgery. Endoscopic thoracic sympathectomy (ETS) cuts the sympathetic chain governing palms to stop palmar sweating \u2014 approximately 30-50% of patients develop compensatory hyperhidrosis (significantly increased sweating in other areas like the back, abdomen, thighs to compensate). Botulinum toxin only blocks sweat glands in the injected area \u2014 without altering overall sympathetic signaling \u2014 sweat glands elsewhere are completely unaffected. Injecting axillae only stops axillary sweating, injecting palms only stops palmar sweating \u2014 precise selective antiperspirant with zero compensatory risk. This is also why botulinum toxin can be repeatedly injected and used at multiple sites simultaneously safely \u2014 palms + axillae + soles can be injected the same day without interference.\"}}, {\"@type\": \"Question\", \"name\": \"How long do Botox antiperspirant results last? How often do I need injections?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Duration varies by site and individual: Axillae \u2014 antiperspirant effect typically lasts 7-9 months (axillary sweat glands are most sensitive to botulinum toxin with slower metabolism); Palms \u2014 6-8 months; Soles \u2014 6-7 months (thick plantar stratum corneum affects drug diffusion). The first year typically requires 2 injections (6-7 month intervals), potentially extending to once yearly in the second year (some patients report cumulative duration extension with repeated injections \u2014 possibly from partial sweat gland atrophy after prolonged inhibition). Rappoel recommends: 2-week post-injection follow-up to assess \u2014 if satisfactory (70%+ sweat reduction), schedule the second injection at 6 months; if suboptimal (under 50% reduction), dose increase or protocol adjustment may be needed. Twice-yearly injections maintain year-round dryness.\"}}, {\"@type\": \"Question\", \"name\": \"Are there contraindications for Botox hyperhidrosis treatment? Who is not suitable?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Contraindicated groups include: (1) Pregnant and breastfeeding women \u2014 while injection doses are small and locally acting, pregnancy injection is not recommended for safety. (2) Those allergic to botulinum toxin or excipients \u2014 extremely rare but requires confirmation. (3) Active infection at injection sites \u2014 such as axillary folliculitis or skin infection; must be treated before injection. (4) Neuromuscular disease patients \u2014 such as myasthenia gravis, Eaton-Lambert syndrome \u2014 botulinum toxin may exacerbate symptoms. (5) Coagulation disorders \u2014 discontinue anticoagulants (e.g., aspirin) 1 week before injection. Suitable candidates: (1) Moderate-to-severe primary focal hyperhidrosis (sweating significantly impacting social and work life). (2) Those unresponsive to or intolerant of antiperspirants. (3) Those unwilling to undergo sympathectomy or with post-surgical compensatory hyperhidrosis. Rappoel conducts detailed consultation and assessment before injection to ensure safe applicability.\"}}]}<\/script><\/p>\n<style>\n*{box-sizing:border-box;margin:0;padding:0}\nbody{font-family:'PingFang SC','Noto Sans KR',sans-serif;background:#fffcf7;color:#3d2e1e;line-height:1.8}\n.wrap{max-width:677px;margin:0 auto;padding:32px 20px 60px}\n.banner{background:#FFF8EC;text-align:center;padding:36px 20px 28px;margin-bottom:36px;border-bottom:1px solid #e8d5c0}\n.banner-tag{font-size:11px;letter-spacing:3px;color:#8B7355;text-transform:uppercase;margin-bottom:12px}\n.banner h1{font-size:24px;color:#3d2e1e;line-height:1.4;margin-bottom:12px}\n.banner .sub{font-size:13px;color:#6b5240;line-height:1.7}\nh2{font-size:19px;color:#3d2e1e;margin:32px 0 14px;padding-bottom:8px;border-bottom:1px solid #e8d5c0}\nh3{font-size:16px;color:#3d2e1e;margin:22px 0 10px}\np{font-size:15px;color:#555;line-height:1.9;margin-bottom:14px}\n.highlight{background:#fff;border:1px solid #f0e8dc;border-left:3px solid #D4A574;padding:16px 20px;margin:22px 0;border-radius:0 6px 6px 0}\n.highlight p{margin:0;font-size:14px;color:#6b5240}\n.card{background:#F5E6C8;border:1px solid #e8d5c0;border-radius:8px;padding:18px 22px;margin:16px 0}\n.card-title{font-size:13px;font-weight:700;color:#3d2e1e;margin-bottom:6px}\n.card p{font-size:14px;margin:0}\n.faq-item{margin:14px 0;border-bottom:1px solid #f0e8dc;padding-bottom:14px}\n.faq-q{font-weight:700;color:#3d2e1e;font-size:15px;margin-bottom:6px}\n.faq-a{font-size:14px;color:#555;line-height:1.8}\n.cta{background:#F5E6C8;text-align:center;padding:32px 20px;margin-top:40px;border-radius:8px}\n.cta h3{font-size:17px;color:#3d2e1e;margin-bottom:8px}\n.cta p{font-size:13px;color:#6b5240;margin-bottom:4px}\nimg{max-width:100%;height:auto;display:block;margin:20px auto;border-radius:6px}\nul,ol{padding-left:22px;margin-bottom:14px}\nli{font-size:15px;color:#555;line-height:1.9;margin-bottom:4px}\n.schema-block{display:none}\n@media(max-width:600px){.wrap{padding:20px 14px 40px}.banner h1{font-size:20px}}\n<\/style>\n<p><\/head><br \/>\n<body><\/p>\n<div class=\"wrap\">\n<div class=\"banner\">\n<div class=\"banner-tag\">Botox<\/div>\n<h1>Botox Hyperhidrosis Treatment in Seoul: Coretox Injection for Excessive Sweating at Rappoel Dermatology Gangnam<\/h1>\n<div class=\"sub\">Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts, foot sweat keeping shoes damp? Rappoel Dermatology uses Coretox botulinum toxin injection \u2014 precisely blocking sweat gland nerve signals, results in 5-7 days lasting 6-9 months<\/div>\n<\/p><\/div>\n<p>Hyperhidrosis is a severely underestimated invisible affliction \u2014 not painful, itchy, or life-threatening, but its negative impact on social, professional, and psychological well-being may exceed many visible conditions. Primary focal hyperhidrosis affects approximately 3% of the global population, typically onset at puberty and persisting lifelong. The distressing scenarios are everywhere: the other person feeling your cold damp palm during a handshake, underarm sweat stains spreading in circles on your shirt during important meetings, constant worry when wearing light-colored clothing, foot sweat odor embarrassment when removing shoes, sweat drops on keyboard screens, fingers slipping on phones… These accumulated scenarios severely undermine self-confidence. The root cause of hyperhidrosis lies in overactive sweat glands \u2014 not from deficiency or weakness, but from hyperactive sympathetic nerve signals governing sweat glands. Rappoel Dermatology near Gangnam Station, Seoul, uses Coretox botulinum toxin injection \u2014 temporarily switching off overactive sweat glands by blocking acetylcholine release, providing a safe and highly effective antiperspirant solution.<\/p>\n<h2>Scientific Mechanism of Hyperhidrosis \u2014 Not Weakness, But Neural Hyperactivity<\/h2>\n<ul>\n<li><strong>Sweat gland innervation:<\/strong> The human body has approximately 2-4 million sweat glands, concentrated in palms, soles, axillae, and forehead. Sweat glands are sympathetically innervated \u2014 sympathetic nerve terminals release acetylcholine (ACh), which binds muscarinic receptors on sweat glands triggering sweat secretion. Normally this system activates for thermoregulation during exercise or heat; hyperhidrosis patients’ sympathetic nerves continuously release excess ACh at normal temperatures<\/li>\n<li><strong>Primary focal hyperhidrosis:<\/strong> The most common type \u2014 presenting as symmetric excessive sweating of palms, axillae, and soles without systemic disease. Pathogenesis involves sympathetic ganglion hyperexcitability with possible genetic predisposition (approximately 30-50% have family history)<\/li>\n<li><strong>Secondary generalized hyperhidrosis:<\/strong> Caused by hyperthyroidism, diabetes, menopause, certain medications, or infections \u2014 requiring treatment of the underlying condition; botulinum toxin is not applicable<\/li>\n<li><strong>Emotional hyperhidrosis:<\/strong> Excessive sweating triggered by stress, anxiety, or social pressure \u2014 related to sympathetic nerve overreaction to emotional stimuli. The vicious cycle: sweating \u2192 anxiety \u2192 more sweating<\/li>\n<li><strong>Starch-iodine test grading:<\/strong> Rappoel uses the Minor’s starch-iodine test to precisely assess sweating area and severity \u2014 iodine solution applied, starch powder sprinkled, sweating areas turn blue-purple, with area and color depth reflecting sweat volume<\/li>\n<\/ul>\n<h2>Coretox Botulinum Toxin Antiperspirant Mechanism<\/h2>\n<ul>\n<li><strong>ACh release blockade:<\/strong> Coretox (Botulinum Toxin Type A) injected into sweat gland-dense areas \u2014 taken up by sympathetic nerve terminals and cleaves SNAP-25 protein (essential for vesicle fusion) \u2014 preventing acetylcholine vesicles from fusing with the cell membrane for release \u2014 sweat glands receive no secretion signal and stop producing sweat<\/li>\n<li><strong>Selective antiperspirant:<\/strong> Botulinum toxin only blocks sweat glands in the injected area \u2014 systemic thermoregulation is unaffected (sweat glands outside the injection zone work normally) \u2014 no hyperthermia or compensatory hyperhidrosis elsewhere<\/li>\n<li><strong>Coretox advantages:<\/strong> Manufactured by Korea’s Hugel \u2014 free of animal proteins and lactose (reducing allergy risk), low diffusion (minimal spread from injection point, minimizing impact on surrounding muscles \u2014 particularly important for palm injections to avoid hand muscle weakness)<\/li>\n<li><strong>5-7 day onset:<\/strong> ACh release is blocked immediately after injection, but already-released ACh requires days for metabolism \u2014 typically 5-7 days for significant sweat reduction (70-90% decrease), with peak antiperspirant effect at 2 weeks<\/li>\n<li><strong>6-9 month duration:<\/strong> Nerve terminals gradually sprout new synapses over 3-6 months restoring ACh release \u2014 antiperspirant effect gradually diminishes. Typically one injection lasts 6-9 months (significant individual variation), with repeated injections potentially extending duration<\/li>\n<\/ul>\n<h2>Rappoel Hyperhidrosis Botox Injection Treatment Protocol<\/h2>\n<ol>\n<li><strong>Sweating assessment and starch-iodine test (15 min):<\/strong> Iodine solution evenly applied to target area (palms\/axillae\/soles) \u2192 starch powder sprinkled \u2192 5-minute wait \u2192 photography documenting sweating area and severity \u2192 marking severe sweating zones as priority injection areas<\/li>\n<li><strong>Disinfection and anesthesia (20 min):<\/strong> Povidone-iodine preparation of target area \u2192 ice packs or vibration anesthesia for palms and soles (more painful injection sites) \u2192 axillae typically require no additional anesthesia (tolerable pain)<\/li>\n<li><strong>Multi-point botulinum toxin injection (15-30 min):<\/strong> 30G\/32G ultra-fine needle for uniform grid injection \u2014 axillae 10-15 points per side, 2 units per point (50-100 units per side total); palms 20-30 points per side, 1-2 units per point (50-100 units per side total); soles 20-30 points per side, 1-2 units per point (50-100 units per side total)<\/li>\n<li><strong>Post-treatment observation and care instructions (10 min):<\/strong> Apply pressure for hemostasis 5 minutes \u2192 instruct no water contact or strenuous exercise for 24 hours \u2192 schedule 2-week follow-up to assess antiperspirant effect<\/li>\n<\/ol>\n<p>Botulinum toxin hyperhidrosis treatment is a life-changing social lifeline \u2014 many patients say after their first treatment, I can finally shake hands confidently or I can finally wear light-colored clothing. Results in 5-7 days, 6-9 months of dryness, with twice-yearly injections for year-round relief. Located 3 minutes from Gangnam Station Exit 10, with seamless English and Chinese consultation.<\/p>\n<h2>Frequently Asked Questions<\/h2>\n<div class=\"faq-item\">\n<div class=\"faq-q\">What’s the difference between Botox antiperspirant and antiperspirant deodorants\/roll-ons?<\/div>\n<div class=\"faq-a\">Completely different action levels: (1) Antiperspirants (aluminum-based) \u2014 form gel-like plugs at sweat duct openings physically blocking sweat discharge. Limited efficacy (20-30% sweat reduction), effective only for mild cases, requires daily use, long-term use may irritate skin and yellow clothing. Prescription-grade 20%+ aluminum chloride is somewhat more effective but may cause irritation and itching. (2) Botulinum toxin injection \u2014 blocks sweat gland secretion signals at the neural level, with 70-90% antiperspirant efficacy, one injection lasting 6-9 months. Suitable for moderate-to-severe hyperhidrosis unresponsive to or intolerant of antiperspirants. Rappoel recommends: mild hyperhidrosis may try prescription-grade aluminum chloride first, then consider botulinum toxin if ineffective or unsatisfactory. Botulinum toxin isn’t a last resort \u2014 for hyperhidrosis severely impacting social life, choosing it directly can rapidly improve quality of life without prolonged ineffective antiperspirant trial periods.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Will Botox injection for palmar hyperhidrosis cause hand numbness or muscle weakness?<\/div>\n<div class=\"faq-a\">With proper technique, no muscle weakness occurs \u2014 but palm injection is indeed the most technically demanding site. Key lies in injection depth: palmar sweat glands are in the mid-dermis (approximately 2-3mm deep), while hand muscles (lumbricals, interossei) are in the deeper subfascial layer. Injection in the mid-dermis acts only on sweat glands without affecting muscles. However, palmar skin is extremely thick and dense with high injection resistance \u2014 requiring experienced physician depth control. Possible mild side effects: (1) Transient hand muscle weakness \u2014 extremely rare, caused by overly deep injection with diffusion to muscle layer, self-resolves in 2-4 weeks. (2) Finger numbness \u2014 extremely rare, from needle contacting digital nerve branches. (3) Significant injection pain \u2014 palms are among the most nerve-dense and painful injection sites; Rappoel uses ice + vibration anesthesia + 32G ultra-fine needles to reduce pain to tolerable levels. Choosing an experienced physician is key to safety.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Will compensatory sweating increase elsewhere after axillary Botox injection?<\/div>\n<div class=\"faq-a\">No \u2014 this is botulinum toxin’s greatest advantage over sympathectomy surgery. Endoscopic thoracic sympathectomy (ETS) cuts the sympathetic chain governing palms to stop palmar sweating \u2014 approximately 30-50% of patients develop compensatory hyperhidrosis (significantly increased sweating in other areas like the back, abdomen, thighs to compensate). Botulinum toxin only blocks sweat glands in the injected area \u2014 without altering overall sympathetic signaling \u2014 sweat glands elsewhere are completely unaffected. Injecting axillae only stops axillary sweating, injecting palms only stops palmar sweating \u2014 precise selective antiperspirant with zero compensatory risk. This is also why botulinum toxin can be repeatedly injected and used at multiple sites simultaneously safely \u2014 palms + axillae + soles can be injected the same day without interference.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">How long do Botox antiperspirant results last? How often do I need injections?<\/div>\n<div class=\"faq-a\">Duration varies by site and individual: Axillae \u2014 antiperspirant effect typically lasts 7-9 months (axillary sweat glands are most sensitive to botulinum toxin with slower metabolism); Palms \u2014 6-8 months; Soles \u2014 6-7 months (thick plantar stratum corneum affects drug diffusion). The first year typically requires 2 injections (6-7 month intervals), potentially extending to once yearly in the second year (some patients report cumulative duration extension with repeated injections \u2014 possibly from partial sweat gland atrophy after prolonged inhibition). Rappoel recommends: 2-week post-injection follow-up to assess \u2014 if satisfactory (70%+ sweat reduction), schedule the second injection at 6 months; if suboptimal (under 50% reduction), dose increase or protocol adjustment may be needed. Twice-yearly injections maintain year-round dryness.<\/div>\n<\/div>\n<div class=\"faq-item\">\n<div class=\"faq-q\">Are there contraindications for Botox hyperhidrosis treatment? Who is not suitable?<\/div>\n<div class=\"faq-a\">Contraindicated groups include: (1) Pregnant and breastfeeding women \u2014 while injection doses are small and locally acting, pregnancy injection is not recommended for safety. (2) Those allergic to botulinum toxin or excipients \u2014 extremely rare but requires confirmation. (3) Active infection at injection sites \u2014 such as axillary folliculitis or skin infection; must be treated before injection. (4) Neuromuscular disease patients \u2014 such as myasthenia gravis, Eaton-Lambert syndrome \u2014 botulinum toxin may exacerbate symptoms. (5) Coagulation disorders \u2014 discontinue anticoagulants (e.g., aspirin) 1 week before injection. Suitable candidates: (1) Moderate-to-severe primary focal hyperhidrosis (sweating significantly impacting social and work life). (2) Those unresponsive to or intolerant of antiperspirants. (3) Those unwilling to undergo sympathectomy or with post-surgical compensatory hyperhidrosis. Rappoel conducts detailed consultation and assessment before injection to ensure safe applicability.<\/div>\n<\/div>\n<div class=\"cta\">\n<h3>Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts? Coretox botulinum toxin hyperhidrosis treatment \u2014 results in 5-7 days, 6-9 months of confident dryness!<\/h3>\n<p>\ud83d\udccd 77, Seocho-daero, Seocho-gu, Seoul, South Korea<\/p>\n<p>\ud83d\udd50 Mon\u2013Fri 10:00\u201319:00 \u00b7 Sat 10:00\u201317:00<\/p>\n<p>\ud83d\udcac WeChat Main: rappoelkr | WeChat Backup: rappoelkr2 | LINE: rappoelkr<\/p>\n<p style=\"margin-top:16px;font-size:13px;color:#8B7355;\">Scan to connect with us<\/p>\n<div style=\"display:flex;justify-content:center;gap:16px;flex-wrap:wrap;margin-top:10px;\">\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Rappoel\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff08\u4e3b\u53f7\uff09-1.png\" alt=\"WeChat Main QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">WeChat (Main)<\/p>\n<\/p><\/div>\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Rappoel\u5fae\u4fe1\u4e8c\u7ef4\u7801\uff08\u5907\u7528\u53f7\uff09-1.png\" alt=\"WeChat Backup QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">WeChat (Backup)<\/p>\n<\/p><\/div>\n<div style=\"text-align:center;\">\n <img decoding=\"async\" src=\"https:\/\/rappoel-clinic.com\/wp-content\/uploads\/2026\/04\/Line\u4e8c\u7ef4\u7801-1.jpg\" alt=\"LINE QR Code\" style=\"width:120px;height:120px;border-radius:6px;\" \/><\/p>\n<p style=\"font-size:11px;color:#6b5240;margin-top:4px;\">LINE<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sweaty palms making handshakes embarrassing, underarm sweat soaking through shirts, foot sweat keeping shoes damp? Rappoel Dermatology uses Coretox botulinum toxin injection \u2014 precisely blocking sweat gland nerve signals, results in 5-7 days lasting 6-9 months<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[66],"tags":[],"class_list":["post-1598","post","type-post","status-publish","format-standard","hentry","category-botox-en"],"_links":{"self":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1598","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/comments?post=1598"}],"version-history":[{"count":1,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1598\/revisions"}],"predecessor-version":[{"id":1600,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/posts\/1598\/revisions\/1600"}],"wp:attachment":[{"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/media?parent=1598"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/categories?post=1598"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rappoel-clinic.com\/en\/wp-json\/wp\/v2\/tags?post=1598"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}